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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objectives: This study was designed to evaluate prescription rate and indirectly the tolerability of antiosychotics using the maintenance rate for 1 year. The study was done in a situation where the patients who were diagnosed with either schizophrenia or schizoaffective disorder were given the antipsychotics and were looked into the prescription rate and the state of use of drugs at first regardless of kind of drugs.
Methods: This was a retrospective, naturalistic study using the data from medical record conducted in both inpatients and outpatients from January 1st in 2002 and June 30th in 2004 with a diagnosis of schizophrenia and schizoaffective disorder as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Patients were evaluated at 3, 6, 9, and 12th months after the onset of medication for the first-drug prescription rate and maintenance rate.
Results: In total, 105 patients were recruited, and 40 out of 105 were male and 65 out of 105 were female. The mean age was 34.71 years old. The number of patients with schizophrenia was 94 and that of schizoaffective disorder was 11. For the prescription rate of first drugs, of total risperidone was 56.2% ; likely, 25.7% for olanzapine ; 10.5% for haloperidol ; 4.8% for quetiapine ; and 2.9% for chlorpromazine. For 1-year maintenance rate, of total, haloperidol was 45.5% ; 33.3% for chlorpromazine ; 22.0% for risperidone ; 14.8% for olanzapine ; and 20.0% for quetiapine.
Conclusion: Overall, atypical antipsychotics were far more prescribed than typical ones(86.7% and 13.3% for atypical and typical anti psychotics respectively). Although atypical antipsychotics were more prescribed than typical ones, the one-year maintenance rate was not higher than typical anti psychotics unlike our expectation that atypical antipsychotics would have better compliance and higher maintenance rate for 1 year under the circumstances with uncontrolled naturalistic conditions. There should be more statistical data available with larger sample size in the future.
Methods: This was a retrospective, naturalistic study using the data from medical record conducted in both inpatients and outpatients from January 1st in 2002 and June 30th in 2004 with a diagnosis of schizophrenia and schizoaffective disorder as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Patients were evaluated at 3, 6, 9, and 12th months after the onset of medication for the first-drug prescription rate and maintenance rate.
Results: In total, 105 patients were recruited, and 40 out of 105 were male and 65 out of 105 were female. The mean age was 34.71 years old. The number of patients with schizophrenia was 94 and that of schizoaffective disorder was 11. For the prescription rate of first drugs, of total risperidone was 56.2% ; likely, 25.7% for olanzapine ; 10.5% for haloperidol ; 4.8% for quetiapine ; and 2.9% for chlorpromazine. For 1-year maintenance rate, of total, haloperidol was 45.5% ; 33.3% for chlorpromazine ; 22.0% for risperidone ; 14.8% for olanzapine ; and 20.0% for quetiapine.
Conclusion: Overall, atypical antipsychotics were far more prescribed than typical ones(86.7% and 13.3% for atypical and typical anti psychotics respectively). Although atypical antipsychotics were more prescribed than typical ones, the one-year maintenance rate was not higher than typical anti psychotics unlike our expectation that atypical antipsychotics would have better compliance and higher maintenance rate for 1 year under the circumstances with uncontrolled naturalistic conditions. There should be more statistical data available with larger sample size in the future.
목차
서론
대상 및 방법
결과
고찰
결론
참고문헌
참고문헌 (50)
참고문헌 신청
1. [학술지(정기간행물)] - Hanns Hippius / 1999 / A historical perspective of clozapine / J Clin Psychiatry (suppl) : S22 ~ S23
2. [학술지(정기간행물)] - Kane LM / 1988 / Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine / Arch Gen Psychiatry 45 : 789 ~ 796
3. [학술지(정기간행물)] - Miller CH / 1998 / The Prevalence of acute extramidal sign and symptoms in patients treated with clozapine, risperidone, and conventional antipsychotics / L Clin Psychiatry 59 : 69 ~ 75
4. [학술지(정기간행물)] - Cuesta MJ / 2001 / Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: A longitudinal study / Schizophr Res 48 : 17 ~ 28
5. [학술지(정기간행물)] - Glazer WM / 2000 / Extrapyramidal side effects, tardive dyskinesia, and the concept of atypicality / J Clin Psychiatry 61 (suppl 3) : S16 ~ S21
2. [학술지(정기간행물)] - Kane LM / 1988 / Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine / Arch Gen Psychiatry 45 : 789 ~ 796
3. [학술지(정기간행물)] - Miller CH / 1998 / The Prevalence of acute extramidal sign and symptoms in patients treated with clozapine, risperidone, and conventional antipsychotics / L Clin Psychiatry 59 : 69 ~ 75
4. [학술지(정기간행물)] - Cuesta MJ / 2001 / Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: A longitudinal study / Schizophr Res 48 : 17 ~ 28
5. [학술지(정기간행물)] - Glazer WM / 2000 / Extrapyramidal side effects, tardive dyskinesia, and the concept of atypicality / J Clin Psychiatry 61 (suppl 3) : S16 ~ S21
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