지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.9
- 수록면
- 347 - 354 (8page)
이용수
초록· 키워드
오류제보하기
The purpose of this study was to evaluate the efficacy of red rose petal extract (RRPE), white rose petal extract (WRPE) and Ganoderma lucidium culture (GLC) in a mouse model of atopic dermatitis induced by ovalbumin (OVA). Female BALB/c mice were intraperitoneally sensitized with OVA (10 ㎍) plus aluminum hydroxide (alum, 4 ㎎) three times weekly and, after 1 week, dermally challenged with patches containing OVA (100 ㎍) for 2 weeks. RRPE, WRPE and GLC were administrated intraperitoneally or orally once a day from day 0 to 35. Intraperitoneal administration of WRPE (5 or 20 ㎎/㎏) inhibited dermal lesions such as erythema/hemorrhage, edema, excoriation and dryness. In particular, oral administration of WRPE (300 ㎎/㎏) markedly attenuated the symptoms as well as epidermal hyperplasia and infiltration of inflammatory cells including mast cells in dermis. In addition, WRPE significantly decreased serum IgE, histamine and interleukin-4 (IL-4) levels. In comparison, despite of inhibitory effects of RRPE and GLC on serum IgE, histamine and/or IL-4 levels, these compounds did not attenuate both the skin symptoms and histopathological findings. Taken together, it is suggested that WRPE could be a potential candidate for the attenuation of chronic atopic dermatitis.
목차
재료 및 방법
결과
고찰
감사의 글
참고문헌
참고문헌 (37)
참고문헌 신청
1. [학술지(정기간행물)] - Akihisa, T. / 2007 / Antiinflammatory and anti-tumor-promoting effects of triterpene acids and steroids from the fungus Ganoderma lucidum / Chem. Biodivers 4 : 224 ~ 231
2. [단행본] - Burns-Naas, L.A. / 2001 / Toxic response of the immune system. In Casarrett & Doull's Toxicology. The Basic Science of Poisons (Klaassen, C.D. ed.), 6th ed / McGraw-Hill : 419 ~ 470
3. [학술지(정기간행물)] - Cao, L.Z. / 2002 / Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides / Immunol. Lett 83 : 163 ~ 169
4. [학술지(정기간행물)] - Caron, G. / 2001 / Histamine induces CD86 expression and chemokine production by human immature dendritic cells / J. Immunol 166 : 6000 ~ 6006
5. [학술지(정기간행물)] - Chien, C.M. / 2004 / Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood / Bioorg. Med. Chem 12 : 5603 ~ 5609
2. [단행본] - Burns-Naas, L.A. / 2001 / Toxic response of the immune system. In Casarrett & Doull's Toxicology. The Basic Science of Poisons (Klaassen, C.D. ed.), 6th ed / McGraw-Hill : 419 ~ 470
3. [학술지(정기간행물)] - Cao, L.Z. / 2002 / Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides / Immunol. Lett 83 : 163 ~ 169
4. [학술지(정기간행물)] - Caron, G. / 2001 / Histamine induces CD86 expression and chemokine production by human immature dendritic cells / J. Immunol 166 : 6000 ~ 6006
5. [학술지(정기간행물)] - Chien, C.M. / 2004 / Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood / Bioorg. Med. Chem 12 : 5603 ~ 5609
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Anti-allergic Effects of Rose Petal Extract and Ganoderma lucidum Culture on Mast Cell-Mediated Allergy Model
Laboratory Animal Research
2008 .03
-
Neuroprotective Effects of a Butanol Fraction of Rosa hybrida Petals in a Middle Cerebral Artery Occlusion Model
Biomolecules & Therapeutics(구 응용약물학회지)
2013 .01
-
황련 추출물의 아토피피부염 유발 생쥐에서 피부손상 완화 효과
동의생리병리학회지
2019 .01
-
아토피피부염 동물 병태 모델에서 아토탕의 개선효과
대한본초학회지(본초분과학회지)
2016 .01
-
Influence of Weight Loss on Severity of Atopic Dermatitis in a 20-Year-Old Female with Atopic Dermatitis
Annals of Dermatology
2018 .01
-
아토피피부염 환자의 발병과 치료에 대한 실태 조사
Allergy Asthma & Respiratory Diseases
2005 .01
-
Effect of Probiotics on the Treatment of Children with Atopic Dermatitis
Annals of Dermatology
2012 .01
-
IgE 매개성, 비 IgE 매개성 소아 아토피피부염 환아의분류에 관한 연구
Allergy Asthma & Respiratory Diseases
2005 .01
-
아토피 피부염 치험 2례
한방안이비인후피부과학회지
2005 .01
-
성인 아토피피부염의 사회경제적 관계에 관한 연구
Allergy Asthma & Respiratory Diseases
2015 .01
-
황련 추출물의 아토피피부염 유발 생쥐에서 피부손상 완화 효과
동의생리병리학회지
2019 .04
-
동물모델에서 cytokine 조율을 통한 한약의 항아토피피부염 효능과 임상적 응용에 대한 고찰
대한본초학회지(본초분과학회지)
2012 .01
-
Inhibitory Effects of Korean Red Ginseng Extract on Atopic Dermatitis in NC/Nga Mice
Laboratory Animal Research
2010 .09
-
소아.청소년에서 아토피 피부염과 주의력결핍과잉행동장애와의 관계
정신신체의학
2006 .01
-
Influences of Environmental Chemicals on Atopic Dermatitis
Toxicological Research
2015 .06
-
Efficacy of Korean Red Ginseng in the Treatment of Atopic Dermatitis
Journal of Ginseng Research
2011 .06
-
감잎(？葉) 추출물의 채취시기에 따른 항산화 활성 변화 및 아토피성 피부염 개선효과
대한본초학회지(본초분과학회지)
2012 .01
-
아토피피부염 환아에서 요중 Leukotriene E4 와 혈청 Eosionphil Cationic Protein과 임상적 활동성과의 상관관계
천식 및 알레르기
2004 .01
-
아토피피부염 치료의 최신 경향
Allergy Asthma & Respiratory Diseases
2009 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
BALB/c mice에서 quercetin의 경구투여가 picryl chloride로 유발된 접촉성 피부 알레르기의 예방에 미치는 영향
김형진
,
정지윤
생명과학회지
2009
.10
Comparative Evaluation of Animal Models for Atopic Dermatitis in NC/Nga Mice
Jun-Won Yun
,
Hyuk Kim
,
Hyun-Jin Kang
외 2명
Laboratory Animal Research
2008
.03
Anti-allergic Effects of Rose Petal Extract and Ganoderma lucidum Culture on Mast Cell-Mediated Allergy Model
Sang-Chul Kwon
,
Sunhee Shin
,
Jeong Hee Jeon
외 7명
Laboratory Animal Research
2008
.03
최근 본 자료
댓글(0)
0