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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.12
- 수록면
- 343 - 347 (5page)
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초록· 키워드
오류제보하기
The ethanol extracts from bark of red pine, Pinus densiflora Siebold et Zuccarini, was examined for single-dose and seven-day repeated-dose toxicity with Sprague-Dawley rats. The single oral dose of the extracts at 5000 ㎎/㎏ did not produce mortality or abnormal gross appearance of the internal organs of rats. In seven-day repeated-dose toxicity study, the extracts administered at doses of 100, 1000, or 5000 ㎎/㎏ for 7 days. There were no significant changes of body weights and organ weights during the experimental period. Hematological analysis and clinical blood chemistry have no revealed toxicity effect of the ethanol extracts from bark of Pinus densiflora. Pathologically, neither gross abnormalities nor histopathological changes observed between controls and treated rats both sexes. Collectively, these data suggest that the ethanol extracts from bark of Pinus densiflora have a high margin of safety.
목차
Material and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (10)
참고문헌 신청
1. [학술지(정기간행물)] - / 1995 / Animal clinical pathology : 517 ~ 537
2. [학술지(정기간행물)] - / 2006 / In vivo antioxidant activityof procyanidin-rich extracts from grape seed and pine bark in rats 76 : 22 ~ 27
3. [학술지(정기간행물)] - / / Chemical composition of pine sproutes and pine neddles for theproduction of pine sprout tea : 274 ~ 11 276
4. [학술지(정기간행물)] - / 1997 / Plasma triglyceride decreasing components of pine nedles 20 : 656 ~ 661
5. [학술지(정기간행물)] - / 2006 / Activation of murine peritoneal macrophages by water soluble extracts of Bursaphelenchus xylophilus a pine wood nematode 70 : 203 ~ 210
2. [학술지(정기간행물)] - / 2006 / In vivo antioxidant activityof procyanidin-rich extracts from grape seed and pine bark in rats 76 : 22 ~ 27
3. [학술지(정기간행물)] - / / Chemical composition of pine sproutes and pine neddles for theproduction of pine sprout tea : 274 ~ 11 276
4. [학술지(정기간행물)] - / 1997 / Plasma triglyceride decreasing components of pine nedles 20 : 656 ~ 661
5. [학술지(정기간행물)] - / 2006 / Activation of murine peritoneal macrophages by water soluble extracts of Bursaphelenchus xylophilus a pine wood nematode 70 : 203 ~ 210
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UCI(KEPA) : I410-ECN-0101-2009-510-016356161