지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.6
- 수록면
- 157 - 163 (7page)
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초록· 키워드
오류제보하기
The improvement efficacies of Erinacol<SUP>®</SUP>, water extract of Hericium erinacium cultivated with Artemisia iwayomogi, in comparison with those of Artemisia iwayomogi extract (AIE), on alcoholic hangover and immune function were investigated via the effects on ethanol overdosage and nitric oxide (NO) production from macrophages, respectively. Low doses (11-33 ㎎/㎏) of Erinacol<SUP>®</SUP> reduced the peak blood concentration and enhanced the clearance of alcohol and acetaldehyde, which was superior to the effects of high doses (100-300 ㎎/㎏) of Erinacol<SUP>®</SUP>, AlE (300 ㎎/㎏) and reference C, a commercial product (3 ㎖/㎏). On the other hand, both Erinacol<SUP>®</SUP> (32-1,000 ㎍/㎖) and AIE (100-1,000 ㎍/㎖) greatly enhanced NO production from macrophages only in the presence of interferon-γ, wherein Erinacol<SUP>®</SUP> exerted a higher efficacy than AIE, although Erinacol<SUP>®</SUP> was more cytotoxic to macrophages at high concentrations. Taken together, it is proposed that Erinacol<SUP>®</SUP> could be a promising candidate for the improvement of alcoholic hangover and immune function.
목차
Materials and Methods
Results and Discussion
Acknowledgment
References
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UCI(KEPA) : I410-ECN-0101-2009-510-016362949