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자료유형
학술저널
저자정보
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.31 No.3
발행연도
2007.9
수록면
117 - 126 (10page)

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Ginseng, the root of Panax species, a well-known herbal medicine has been used as a traditional medicine for thousands of years and is now a popular and worldwide used natural medicine. Ginseng has been used primarily as a tonic to invigorate weak bodies to help the restoration of homeostasis in a wide range of pathological conditions such as cardiovascular diseases, cancer, immune deficiency and hepatotoxicity. Although conclusive clinical data in humans is still missing, recent research results have suggested that some of the active ingredients ginseng exert beneficial effects on central nervous system (CNS) disorders and neurodegenerative diseases, suggesting it could be used in treatment of psychotic disorders. Data from neural cell cultures and animal studies contribute to the understanding of these mechanisms that involve inhibitory effects on stress-induced corticosterone level increasing and modulating of neurontransmitters, reducing Ca²? over-influx, scavenging of free radicals and counteracting excitotoxicity. In this review, we focused on recently reported medicinal effects of ginseng and summarized the possibility of its applications on psychotic disorders.

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Abstract
INTRODUCTION
EFFECTS OF GINSENG ON PSYCHOTIC DISORDERS
POSSIBLE MECHANISMS
CONCLUSION AND FUTURE PERSPECTIVES
ACKNOWLEDGEMENT
REFERENCES

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