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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.9
- 수록면
- 263 - 268 (6page)
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This study was carried out to evaluate the cytotoxic effect of phenolic compound on normal NIH 3T3 fibrolasts. The colorimetric assay for phenol compound, syringic acid was performed by MTT assay or XTT assay. MTT or XTT assays are known as a very sensitive method in measuring the cytotoxic effect of chemical agents in vitro. In the present study, syringic acid on normal NIH 3T3 fibroblasts did not show any cytotoxicity for MTT assay or XTT assay compared with control after cells were treated with various concentrations of syringic acid for 48 hours. MTT?? and XTT?? were 3,340.9 μM and 2,462.4 μM of syringic acid, respectively. From the above the results, it is suggested that phenolic compound of syringic acid did not have any cytotoxicity on normal NIH 3T3 fibroblasts.
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감사의 글
REFERENCES
참고문헌 (18)
참고문헌 신청
[학술지(정기간행물)] - Andrade PB, / 2001. / Analysis of phenolic compounds in Spanish Albrarino and Portuguese Alvarinho and Loureiro wines by capillary zone electrophoresis and high-performance liquid chromatography. 22 : 1568 ~ 1572
[학술지(정기간행물)] - / / Matin-Alcuacil N. Comparisons oftwo in vitro cytotoxicity assay. The neutral red andtetrazolium MTT tests. Toxicol In Vitro. 1988. 2 : 1 ~ 8
[학술지(정기간행물)] - Cha HJ, / 1996. / Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibroblastoma cells. : 2281 ~ 2284.
[학술지(정기간행물)] - Constabel CP, / 2000. / Nucleotide, Free in PMC, Protein Polyphenol oxidase from hybrid poplar. Cloning and expression in response to wounding and herbivory. 124 : 285 ~ 295
[학술지(정기간행물)] - Duthie GC, Alan. / 2000. / Plant-derived phenolic antioxidants. Current Opinion in Clinical Nutrition and Metabolic Care. : 447 ~ 451
[학술지(정기간행물)] - / / Matin-Alcuacil N. Comparisons oftwo in vitro cytotoxicity assay. The neutral red andtetrazolium MTT tests. Toxicol In Vitro. 1988. 2 : 1 ~ 8
[학술지(정기간행물)] - Cha HJ, / 1996. / Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibroblastoma cells. : 2281 ~ 2284.
[학술지(정기간행물)] - Constabel CP, / 2000. / Nucleotide, Free in PMC, Protein Polyphenol oxidase from hybrid poplar. Cloning and expression in response to wounding and herbivory. 124 : 285 ~ 295
[학술지(정기간행물)] - Duthie GC, Alan. / 2000. / Plant-derived phenolic antioxidants. Current Opinion in Clinical Nutrition and Metabolic Care. : 447 ~ 451
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