지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
In the biological world, there are a number of ecological fights for survival between each organism such as plants, animals and microorganism. In such events, an organism can use its natural bioactive products as defence agent against other organisms. Furthermore, natural bioactive products can be utilized for medicine or functional food. Recently, we investigate the effect of Monascus pigment extracted from a fungus, Monascus anke, on the alcohol metabolism and blood lipid profile. In the present study, it is observed that Monascus pigment supplemented dietary may have a hepatoprotective effect on rat’s liver damage induced with CCl₄. By treatment with CCl₄ (3 times, I.P), liver damage was reduced more in the rats fed 2% Monascus pigment extract supplemented diet than those fed standard diet, based on the serum levels of alanine aminotransferase, microsomal glucose-6-phosphatse activity and hepaic malondialdehyde content. On the other hand, oxygen free radical generating enzymes, hepatic P-450 dependent aniline hydroxylase, xanthine oxidase, and oxygen free radical scavenging enzymes, hepatic glutathione S-transferase, catalase, superoxide dismutase activities were generally higher both in CCl₄ treated group and control fed 2% Monascus pigment extract supplemented diet than those fed standard diet. In conclusion, the rats fed 2% Monascus pigment extract supplemented diet showed more reduced liver damage than those fed standard diet, which may be due to the acceleration of oxygen free radical metabolism.
목차
영어 초록
서론
재료 및 방법
결과
고찰
참고문헌
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effect of p-Phenylenediamine Application to Rat Skim on the Liver Oxygen Free Radical Systems
대한의생명과학회지
2003 .06
-
급성 간손상의 실험동물 피부조직에 있어서 Oxygen Free Radical의 대사효소 활성 변동
대한의생명과학회지
1999 .06
-
사상성 곰팡이 (Monascus sp.) 유래 항암 물질의 탐색
동의생리병리학회지
2005 .06
-
CCl₄에 의한 간손상 정도 차이에 따른 Xylene 대사 변동
Toxicological Research
1999 .09
-
CCl4에 의한 간손상 모델 실험동물에 있어서 cyclohexane 투여가 혈청 glutathione S-transferase 활성에 미치는 영향
한국환경보건학회지
2003 .01
-
Comparative Studies on the Therapeutic Effect and Withdrawal Reversing Phenomenon of GODEXⓇ in CCl₄-Liver Injury Model in Rats
한국실험동물학회 학술발표대회 논문집
2003 .06
-
Extracts of Codonopsis lanceolata Decrease CCl₄-Induced Hepatotoxicity on High Fat Diet in Rats
대한의생명과학회지
2004 .12
-
홍화씨 식이가 사 염화탄소에 의한 랫트 간손상에 미치는 영향: 병리조직학적 관찰
한국수의병리학회지
2001 .01
-
Effects of Liquid Culture of Agaricus blazei Murill on Protein, Mineral Levels and Enzyme Activities in Rats
대한의생명과학회지
2004 .06
-
Development of the Hypotensive-Food Materials with the Fungal Genus Monascus
한국실험동물학회 학술발표대회 논문집
2002 .06
-
CCl₄전처치한 흰주에 Cyclohexane 투여가 간손상에 미치는 영향
Toxicological Research
2003 .06
-
사역산합평위산가인진택사방(四逆散合平胃散加茵蔯澤瀉方)이 $CCl_4$에 의한 흰쥐의 간(肝) 손상에 미치는 영향
대한본초학회지(본초분과학회지)
2006 .01
-
Serum Levels of Xanthine Oxidase Activities in Cyclohexanone-Treated Rats Pretreated with Carbon Tetrachloride
대한의생명과학회지
2002 .03
-
아토피피부염 환자에서 혈중 케모카인 농도와 SCORAD 점수의 상관관계
Allergy Asthma & Respiratory Diseases
2007 .01
-
Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats
Journal of Ginseng Research
2017 .07
-
인진호탕가웅담(茵蔯蒿湯加熊膽)의 경구투여(經口投與)가 $CCl_4$ 투여(投與)로 유발(誘發)된 간경변(肝硬變)에 미치는 영향(影響)
대한한의학방제학회지
2001 .01
-
Effect of Cyclohexanone Treatment on the Serum Levels of Glutathione S-Transferase Activities in Acute Liver Damaged Rats
대한의생명과학회지
2001 .12
-
Hepatoprotective Effects of Polysaccharides Isolated from Phellinus gilvus Against Carbon Tetrachloride-induced Liver Injury in Rats
Toxicological Research
2009 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-510-017341106