지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The Melanocortin-4 receptor gene (MC4R) regulates the energy balance and the genetic basis of obesity. A polymorphism in the porcine melanocortin-4 receptor has previously shown to be associated with growth, fat deposition and feed intake. In this study, the polymorphism of the gene was studied in several pig breeds of Duroc, Landrace, Berkshire, and Yorkshire. The results showed that the frequencies of MC4R genotype varied among those breeds. Association analyses were also performed between the MC4R polymorphism and average daily gain, feed conversion ratio, backfat thickness and lean percentage phenotypes. The results strongly support that the MC4R polymorphism can be used DNA marker selection indicator for economically important traits for pig breeding program in Korea.
목차
Abstract
재료 및 방법
결과 및 고찰
요약
감사의 글
참고문헌
참고문헌 (10)
참고문헌 신청
Farooqi, I. S., J. M. Keogh,. G. S. Yeo, E. J. Lank, T. Cheetham and S. O'Rahilly. 2003. Clinical spectrum of obesity and mutations in the melanocrtin-4 receptor gene. N. Engl. J. Me. 348, 1085-1089.
Hernandez-Sanchez, J., P. Visscher, G. S. Plastow and C. Haley. 2003. Candidate gene analysis for quantitative traits using the transmission disequilibrium test: the example of the melancortin-4 receptor in pigs. Genetice. 164, 637-644.
Hinney, A. S. Hohmann, F. Geller , C. Vogel, C. Hess, AK. Wermter, B. Brokamp, H. Goldschmidt, W. Siegfried, H. Remschmidt, H. Schafer, T. Gudermann, and J. Hebebrand. 2003. Melanocortin-4 receptor gene: case-control study and transmission disequilibrium
Houston, R. D., N. D. Cameron and K. A. Rance. 2004. A melanocortin-4 receptor (MC4R) polymorphism is associated with performance traits in divergently selected Large White pig populations. Anim. Genet. 35, 386-390.
Kim, K. S., J. M. Reecy, W. H. Hsu, L. L. Anderson and M. F. Rothschild. 2004. Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pig. Domestic Anim Endocrinol. 26, 75-86.
Hernandez-Sanchez, J., P. Visscher, G. S. Plastow and C. Haley. 2003. Candidate gene analysis for quantitative traits using the transmission disequilibrium test: the example of the melancortin-4 receptor in pigs. Genetice. 164, 637-644.
Hinney, A. S. Hohmann, F. Geller , C. Vogel, C. Hess, AK. Wermter, B. Brokamp, H. Goldschmidt, W. Siegfried, H. Remschmidt, H. Schafer, T. Gudermann, and J. Hebebrand. 2003. Melanocortin-4 receptor gene: case-control study and transmission disequilibrium
Houston, R. D., N. D. Cameron and K. A. Rance. 2004. A melanocortin-4 receptor (MC4R) polymorphism is associated with performance traits in divergently selected Large White pig populations. Anim. Genet. 35, 386-390.
Kim, K. S., J. M. Reecy, W. H. Hsu, L. L. Anderson and M. F. Rothschild. 2004. Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pig. Domestic Anim Endocrinol. 26, 75-86.
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UCI(KEPA) : I410-ECN-0101-2009-470-015375996