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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.4 No.2
- 발행연도
- 1999.6
- 수록면
- 125 - 129 (5page)
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The influence of dietary cholesterol on phospholipid metabolism in rat liver microsomes was studied in rats fed a diet containing fish oil (FO) or beef tallow (BT). The hepatic phospholipid content decreased whereas hepatic triglyceride and cholesterol increased significantly in both groups after cholesterol supplementation. Plasma concentrations of phospholipid and triglyceride increased with cholesterol supplement in both groups while cholesterol decreased only moderately in the FO group. Dietary cholesterol affected microsomal phospholipids in liver; the proportion of phosphatidylcholine decreased in the FO group, and it also slightly decreased in the BT group at the expense of phosphatidylethanolamine. The activity of CTP:phosphocholine cytidylyltransferase, the rate-limiting enzyme of phosphatidylcholine synthesis, increased in hepatic microsomes whereas it decreased in hepatic cytosol of both groups by cholesterol supplementation. In conclusion, these results indicate that the dietary cholesterol profoundly influences phospholipid metabolism in the rat liver.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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