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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한기계학회 Journal of Mechanical Science and Technology Journal of Mechanical Science and Technology Vol.19 No.5
- 발행연도
- 2005.5
- 수록면
- 1,158 - 1,168 (11page)
이용수
초록· 키워드
오류제보하기
A shunt from the left ventricle to the left anterior descending artery is being developed for coronary artery occlusive disease. in which the shunt or conduit connects the the left ventricle (L V) with the diseased artery directly at a point distal to the obstruction. To aid in assessing and optimizing its benefit. a computational model of the cardiovascular system was developed and used to explore various design conditions. Computational fluid dynamic analysis for the shunt hemodynamics was also done using a commercial finite element package. Simulation results indicate that in complete left anterior descending artery (LAD) occlusion, now can be returned to approximately 65% of normal. if the conduit resistance is equal for forward and reverse now. The net coronary now can increase to 80% when the backflow resistance is infinite. The increases in now rate produced by asymmetric now resistance are enhanced considerably for a partial LAD obstruction. since the primary effect of resistance asymmetry is to prevent leakage back into the ventricle during diastole. Increased arterial compliance has little effect on net flow with a symmetric shunt, but considerably augments it when the resistance is asymmetric. The computational results suggest that an LV-LAD conduit will be beneficial when the resistance due to artery stenosis exceeds 27 PRU, if the resistance is symmetric. Fluid dynamic simulations for the shunt flow show that a recirculating region generated near the junction of the coronary artery with the bypass shunt. The secondary flow is induced at the cutting plane perpendicular to the axis direction and it is in the attenuated of coronary artery.
목차
Abstract
1. Introduction
2. Methods
3. Results and Discussion
4. Conclusions
References
Appendix
참고문헌 (13)
참고문헌 신청
Bathe, K. J., Zhang, H., Wang, M. M., 1995, "Finite Element Analysis of Incompressible and Compressible Fluid Flows with Free Surfaces and Structural Interactions," Computers and Structures, 56, No. 2/3, pp.193~213.
Beyar, R., Guerci, A. D., Halperin, H. R., Tsitlik, J. E., Weisfeldt, M. L., 1989, "Intermittent Coronary Sinus Occlusion After Coronary Arterial Ligation Results in Venous Retroperfusion," Circ Res, Vol.65, No.3, pp.695~707.
Beyar, R., Caminker, R., Manor, D. and Sideman, S., 1993, "Coronary Flow Patterns in Normal and Ischemic Hearts: Transmyocardial and Artery to Vein Distribution," Ann Biomed Eng, Vol.21, No.4, pp.435~458.
Boekstegers, P., Raake, P., Al Ghobainy, R., Horstkotte, J., Hinkel, R., Sandner, T., Wichels, R., Meisner, F., Thein, E., March, K., Boehm, D. and Reichenspurner, H., 2002, "Stent-based Approach for Ventricle-to-coronary Artery Bypass," Circulation, Vol.
de Zeeuw, S., Borst, C., Grundeman, P. F., 2004, "Myocardial Blood Supply Through a Direct Left Ventricle-coronary Artery Shunt is not Aided by Augmented Coronary Capacitance," J Thorac Cardiovasc Surg, Vol.127, No.6, pp.1751~1758.
Beyar, R., Guerci, A. D., Halperin, H. R., Tsitlik, J. E., Weisfeldt, M. L., 1989, "Intermittent Coronary Sinus Occlusion After Coronary Arterial Ligation Results in Venous Retroperfusion," Circ Res, Vol.65, No.3, pp.695~707.
Beyar, R., Caminker, R., Manor, D. and Sideman, S., 1993, "Coronary Flow Patterns in Normal and Ischemic Hearts: Transmyocardial and Artery to Vein Distribution," Ann Biomed Eng, Vol.21, No.4, pp.435~458.
Boekstegers, P., Raake, P., Al Ghobainy, R., Horstkotte, J., Hinkel, R., Sandner, T., Wichels, R., Meisner, F., Thein, E., March, K., Boehm, D. and Reichenspurner, H., 2002, "Stent-based Approach for Ventricle-to-coronary Artery Bypass," Circulation, Vol.
de Zeeuw, S., Borst, C., Grundeman, P. F., 2004, "Myocardial Blood Supply Through a Direct Left Ventricle-coronary Artery Shunt is not Aided by Augmented Coronary Capacitance," J Thorac Cardiovasc Surg, Vol.127, No.6, pp.1751~1758.
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