지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The organization of eukayotic chromatin into specific conformation that are associated with transcription, replication, reapir and other nuclear processes are achieved via a series of DNA-protein interaction. These interactions are mediated by a range of DNA-binding domains such as SAP domain et al. By searching S. pombe genomic DNA database, we have found a gene named SAPuvs (SAP UV Sensitive) whose amino acid sequence is in part similar to SAP domain of Arabidopsis poly (ADP-ribose) polymerase and Ku70. Knock-out cell of S. pombe SAPuvs gene was constructed using Ura4 as a selection marker. Survival analysis of knock-out cell indicated that treatment with UV significantly reduces the survival compared to wild type cell. Potentiation of MMS-induced cytotoxicity by 3AB post-treatment was observed in wild type cells, but not in knock-out cells. These data suggested that the protein encoded by SAPuvs gene is associated with chromatin reorganization during DNA repair.
목차
Abstract
서 론
재료 및 방법
결 과
고 찰
요 약
감사의 글
참 고 문 헌
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effect of the pat, fk, stpk Gene Knock-out and mdh Gene Knock-in on Mannitol Production in Leuconostoc mesenteroides
Journal of Microbiology and Biotechnology
2018 .01
-
Characterization of HRD3, a Schizosaccharomyces pombe Gene Involved in DNA Repair and Cell Viability
Korean journal of biological sciences
2003 .01
-
Effects of 3-Aminobenzamide on DNA Strand Breaks and Excision Repair in CHO cells Exposed to Methyl Methanesulfonate and Ultraviolet-light
동물학회지
1983 .01
-
Characterization of UV-damaged repair genes in cells
Journal of Life Science
2000 .10
-
Characterization of Structural Variations in the Context of 3D Chromatin Structure
Molecules and Cells
2019 .01
-
분열형 효모에서 mas3+ 유전자의 세포내 기능 연구
생명과학회지
2005 .02
-
Study on Expression and Characterization of HRD3 Gene Related DNA Repair from Eukaryotic Cells
생명과학회지
2004 .04
-
Analysis of Gene Expression upon DNA Damage in Arabidopsis
식물학회지
2006 .01
-
Revealing Regulatory Networks of DNA Repair Genes in S. Cerevisiae
Bioinformatics and Biosystems
2007 .01
-
3C (Chromatin Conformation Capture); A Technique to Study Chromatin Organization
생명과학회지
2012 .11
-
Isolation and Characterization of New Family Genes of DNA Damage in Fission Yeast
한국동물학회 학술대회
1999 .01
-
Characterization of DNA Repair Gnes from Fission Yeast Schizosaccharomyces pombe
한국동물학회 학술대회
1999 .01
-
Retrieving Protein Domain Encoding DNA Sequences Automatically Through Database Cross-referencing
Bioinformatics and Biosystems
2006 .01
-
MCF-7 세포주의 ？선에 의한 DNA 손상 반응 유전자 발현 양상의 분석
환경생물
2005 .01
-
Improved DNA Extraction Method for Molecular Diagnosis from Smaller numbers of Cells
대한임상검사과학회지
2014 .01
-
Characterization of UV-Inducible Gene(UVI-155) in Schizosaccharomyces pombe
생명과학회지
2006 .02
-
유전자 발현 조절과 DNA 3차원적 구조와의 관계
한국식물학회 심포지움
1987 .01
-
E2F1 facilitates DNA break repair by localizing to break sites and enhancing the expression of homologous recombination factors
Experimental and Molecular Medicine
2019 .01
-
DNA-PK-null 세포주의 adriamycin 처리에 의한 G₂/M 세포주기 변화
생명과학회지
2003 .06
-
Isolation and Characterization of UV-Inducible Genes from Schizosaccharomyces pombe
한국동물학회 학술대회
2001 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-470-014219762