지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2003.9
- 수록면
- 211 - 215 (5page)
이용수
초록· 키워드
오류제보하기
This study was carried out to investigate the acute oral toxicity of a crude extract derived from fruiting body of Phellinus gilvus (PGE) using male and female SD rats. Groups consisted of five male and female rats were treated with a single dose of the test substance intragastrically at 0, 500, 1,000, 2,000, and 5,000 mg/kg, respectively. Clinical signs, body weight change, and food and water consumption change were observed for 14 days after administration. No mortality or abnormal clinical signs in animals were shown during the observation period at the dose used in this study. Also there was no difference in net body weight gain, water and food consumption or gross pathological findings at terminal sacrifice among the groups of rat treated with different doses
of the test substance. The results suggested that acute oral toxicity of PGE in rats is very low at the conditions employed in this study and LD50 of PGE was estimated to be over 5,000 mg/ml in
both sexes of rats.
of the test substance. The results suggested that acute oral toxicity of PGE in rats is very low at the conditions employed in this study and LD50 of PGE was estimated to be over 5,000 mg/ml in
both sexes of rats.
목차
ABSTRACT
INTRODUCTION
MATERIAS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Single Oral Dose Toxicity Study of Bamboo Leaf Water Extract in Sprague-Dawley Rats
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2003 .01
-
Single Oral Dose Toxicity Evaluation of CS682, a Fermentation Product of Korean Soil Bacteria, in Rats
Laboratory Animal Research
2007 .12
-
재배 상황버섯 추출물의 경구투여 급성독성 연구
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2001 .01
-
杏仁의 랫트 단회 경구 투여 독성시험
대한한방내과학회지
2012 .01
-
Acute and Repeated 28-Day Oral Dose Toxicity Studies of Thymus vulgaris L. Essential Oil in Rats
Toxicological Research
2019 .07
-
Single Oral Dose Toxicity Test of Low Molecular Weight Fucoidan in Rats
Biomolecules & Therapeutics(구 응용약물학회지)
2009 .01
-
Acute and sub-acute oral toxicity study of multi-mineral compound in rats
한국실험동물학회 학술발표대회 논문집
2019 .07
-
14 Days Repeat Oral Dose Toxicity of Low Molecular Weight Fucoidan in Rats
Biomolecules & Therapeutics(구 응용약물학회지)
2010 .01
-
Acute and repeated dose 26-week oral toxicity study of 20(S)-ginsenoside Rg3 in Kunming mice and Sprague-Dawley rats
Journal of Ginseng Research
2020 .03
-
두릅나무와 황백피의 혼합추출물 P55A의 랫트 및 개에 대한 경구투여 급성독성
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1999 .01
-
Single Oral Toxicity Study of 3-Methoxy-6-Allylthiopyridazine in Rats
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2005 .01
-
Toxicity Study of AS6, a Triterpenoid Derivative: 4-Week Repeated Oral Administration in Rats
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2003 .01
-
GST의 Sprague-Dawley Rat를 이용한 단회 경구투여 독성시험 및 4주 반복 경구투여 용량결정시험
대한한방내과학회지
2013 .01
-
Acute Toxicity of CKD-602, a New Anticancer Agent, in Rats
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2004 .01
-
비 마약성 진통제 DA-5018의 급성독성시험
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1997 .01
-
Single-Dose Oral Toxicity of Fermented Scutellariae Radix Extract in Rats and Dogs
Toxicological Research
2012 .12
-
Acute Toxicity of $P_2$, $B_1$, $T_{0}$, and $O_1$ in Rats and Mice
한국응용약물학회 추계학술발표논문집
1998 .01
-
Acute and Sub-chronic Oral Toxicity Study of Ammonium Persulfate in Spraque-Dawley Rats
Toxicological Research
2009 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-513-013745698