지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2002.12
- 수록면
- 453 - 457 (5page)
이용수
초록· 키워드
오류제보하기
Pemphigus vulgaris is a serious autoimmune disease that forms blisters on mucosa and skin. It is common in people over 60 years of age, and it has a strong genetic tendency, Autoantibodies can be found in intercelluar spaces between epithelial cells, and because of the autoantibodies for desmosomes, desmosomes that connect the squamous epithelial cells are destroyed. In pemphigus vulgaris, oral lesion is almost always present, and it is often present before skin lesions. Oral lesions can be present anywhere in the oral cavity including the mucosa and gingiva. When it is present in the gingiva, it is in a form of desquamative gingivitis. In severe cases, the entire oral mucosa is involved, and various stages of vesicle formation are manifested. In addition, although the treatment of pemphigus vulgaris is relatively successful, the oral lesion is the last to disappear, and periodic deterioration and alleviation of symptoms is common.
Definite diagnosis for pemphigus vulgaris is based on microscopic examinations including direct immunofluorescence, As in most autoimmune diseases, immunosuppressive drugs are used for treatment. The prognosis should be made carefully considering its chronic progression and side effects of long-term medications. With early diagnosis and appropriate treatment during the initial stage of pemphigus vulgaris, wide skin involvement can be controlled, and need for aggressive treatment with undesirable side effects can be reduced.
In this case report, the continuous treatment of a patient with pemphigus vulgaris was observed in consultation with a dermatologist and a general investigation of pemphigus vulgaris is made.
Definite diagnosis for pemphigus vulgaris is based on microscopic examinations including direct immunofluorescence, As in most autoimmune diseases, immunosuppressive drugs are used for treatment. The prognosis should be made carefully considering its chronic progression and side effects of long-term medications. With early diagnosis and appropriate treatment during the initial stage of pemphigus vulgaris, wide skin involvement can be controlled, and need for aggressive treatment with undesirable side effects can be reduced.
In this case report, the continuous treatment of a patient with pemphigus vulgaris was observed in consultation with a dermatologist and a general investigation of pemphigus vulgaris is made.
목차
1. 서론
2. 증례
3. 총괄 및 고찰
4. 결론
참고문헌
ABSTRACT
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UCI(KEPA) : I410-ECN-0101-2009-515-013693322