The rapid change in the business environment and the endless deepening of competitiveness among companies have led many companies to consider business process reengineering(BPR) as a means of improving their performance. However, while only a few companies have succeeded in BPR, most of the efforts made in business process reengineering have been considered to have failed the project because they failed to get the intended results. This shows a lack of connectivity between BPR and Information Systems innovation. Those who have performed BPR will be sympathetic to the fact that BPR and Information System Innovation have the same relationship as both sides of the coin. In order to secure competitive advantage, business process reengineering is necessary, and BPR must be supported by innovation of information system. In other words, no matter how innovative a business process is, if it can not effectively support it through the utilization of information technology, the expected effect of process innovation will be reduced. Accordingly, this paper will present the methodology for BPR and Information system integrated construction for successful BPR performance and information system construction. The proposed methodology is not performed sequentially by implementing BPR consulting methodology and Information System construction methodology, but it is performed simultaneously by integrating BPR Consulting Methodology and Information System Construction methodology. Accordingly, the new methodology for BPR consulting and information system integrated construction will be described in the performing steps, the reflection of BPR consulting results, and the description of success factors, risk factors, and comparisons to improvements. As a verification process, we will use the ViRE(Value-innovative Requirements Engineering) process. This process is the most effective in identifying the value of new customers through performance upgrades and quality improvements in software(systems). In this paper, we will apply the value innovation requirements engineering process that can create value for new customers to the integrated construction methodology of BPR and Information system to redefine the value of our customers. In addition, we will apply the Six Sigma DFSS(Design For Six Sigma) methodology to verify quality and process improvement through quantitative and systematic analysis and verify the success of BPR and information system integration methodology. The integrated Construction methodology of BPR and Information System are presented in practice, and the empirical analysis results are presented, including the results of a questionnaire survey of the system users to verify the validity of the application results.