메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학위논문
저자정보

조민철 (삼육대학교, 삼육대학교 대학원)

지도교수
박명환
발행연도
2017
저작권
삼육대학교 논문은 저작권에 의해 보호받습니다.

이용수0

표지
AI에게 요청하기
추천
검색

이 논문의 연구 히스토리 (2)

초록· 키워드

오류제보하기
Versatile drug delivery devices using nanoporous membranes consisting of gold nanorods and dendrimers have been demonstrated to provide light-triggered on-demand pulsatile release from a reservoir containing highly enriched therapeutics for a real patient’s needs. The drug release rate is directly correlated with the temperature increase and irradiated energy of a near-IR laser in both static and fluidic devices. This biocompatible platform for on-demand control was further confirmed by in vitro experiments. Interestingly, different responses to stimuli were obtained from each drug in the absence and presence of NIR light, indicating the versatile potential of our on-demand drug delivery system in less-invasive therapies requiring multi-drug delivery strategies. The enhanced delivery system will improve therapeutic efficacy and reduce side effects through regulation of plasma drug profiles.

목차

Part Ⅰ: Externally controlled drug release using a gold nanorod contained composite membrane
Contents ⅰ
List of Figures ⅱ
Abstract ⅲ
1. Introduction 1
2. Experimental 5
A. Materials and method 5
B. Preparation of GNRs 6
C. Fabrication of the device and characterization of drug release 7
D. Post-functionalization of a GNR-Den membrane 8
E. In vitro analysis 8
3. Results and discussion 10
4. Conclusion 23
Reference ⅳ
Part Ⅱ: Optically switchable fibrous membrane''s pore size for on-demand drug delivery by thermal-responsive polymer
Contents ⅶ
List of Figures ⅷ
Abstract ⅸ
1. Introduction 23
2. Experimental 26
A. Materials and methods 26
B. Preparation of GNRs 27
C. Synthesis of octa glydicyl polyhedral oligomeric silsequioxane (OG-POSS) 28
D. Fabrication of CA-PNIPAM fiber membrane 28
3. Results and discussion 29
4. Conclusion 37
Reference ⅹ

최근 본 자료

전체보기

댓글(0)

0