지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학위논문
- 저자정보
- 지도교수
- 문재동
- 발행연도
- 2016
- 저작권
- 전남대학교 논문은 저작권에 의해 보호받습니다.
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초록· 키워드
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Objectives
The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery computed tomography angiography (CCTA).
Methods
In this study, 110 male workers participated and underwent a CCTA examination for CAC scoring, which represents coronary artery plaque, and were evaluated for luminal stenosis. All of the subjects were working in the same chemical plant, of whom 70 worked day shifts and 40 worked rotating shifts.
Results
In a multivariate logistic regression analysis, including age, smoking status, alcohol consumption, regular exercise, and waist circumference, shift work was associated with a 2.89-fold increase in the odds of developing coronary plaque compared with day work (odds ratio, 2.89; 95% confidence interval [CI], 1.07?7.82). The association between shift work and coronary plaque was strong after adjustment for age, low-density lipoprotein cholesterol, hypertension, and diabetes mellitus (odds ratio, 2.92; 95% CI, 1.02?8.33). In addition, the number of years of shift work employment was associated with coronary plaque. However, no association was found between shift work and coronary artery stenosis.
Conclusion
Shift work could induce CAD onset via the atherosclerotic process, and shift work employment duration was associated with an increased risk of atherosclerosis in male workers.
The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery computed tomography angiography (CCTA).
Methods
In this study, 110 male workers participated and underwent a CCTA examination for CAC scoring, which represents coronary artery plaque, and were evaluated for luminal stenosis. All of the subjects were working in the same chemical plant, of whom 70 worked day shifts and 40 worked rotating shifts.
Results
In a multivariate logistic regression analysis, including age, smoking status, alcohol consumption, regular exercise, and waist circumference, shift work was associated with a 2.89-fold increase in the odds of developing coronary plaque compared with day work (odds ratio, 2.89; 95% confidence interval [CI], 1.07?7.82). The association between shift work and coronary plaque was strong after adjustment for age, low-density lipoprotein cholesterol, hypertension, and diabetes mellitus (odds ratio, 2.92; 95% CI, 1.02?8.33). In addition, the number of years of shift work employment was associated with coronary plaque. However, no association was found between shift work and coronary artery stenosis.
Conclusion
Shift work could induce CAD onset via the atherosclerotic process, and shift work employment duration was associated with an increased risk of atherosclerosis in male workers.
목차
1. Abstract 12. Introduction 33. Methods 54. Results 105. Discussion 126. References 18
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