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논문 기본 정보

자료유형
학위논문
저자정보

이권수 (영남대학교, 영남대학교 대학원)

지도교수
고영휘
발행연도
2016
저작권
영남대학교 논문은 저작권에 의해 보호받습니다.

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이 논문의 연구 히스토리 (2)

초록· 키워드

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Introduction and objective: Though urodynamic study (UDS) is the current established standard to distinguish between detrusor underactivity (DU) and bladder outlet obstruction (BOO), concerns of patient discomfort and potential complications of catheterization deters its use. We inspected clinical variables to discriminate between DU and BOO in uroflowmetry, which can be more easily performed in clinical practice.
Methods: Total 240 men who both underwent UDS and uroflowmetry were reviewed. The patients were divided into two groups by a single experienced urologist based on UDS outcome; DU (n=111) and BOO (n=129). From uroflowmetry, five variables including max flow rate (Qmax), average flow rate (Qave), voiding volume (VV), post voiding residual urine (PVR), and value of Qmax minus Qave (Delta Q) was obtained. Multivariable analysis including receiver operating characteristic (ROC) curve analysis was performed to identify the important diagnostic predictors.
Results: The mean age (±SD) was 65.3±9.2 years. Except Qave, all uroflowmetry components were significantly different between DU and BOO groups. Delta Q was smaller in DU group (8.71 ml/s vs. 5.26 ml/s, p<0.001). By logistic regression analysis, Delta Q (Exp (B) = 0.648, p<0.001) and PVR (Exp(B) =1.009, p<0.001) significantly discriminate DU and BOO diagnosis. In diagnosing DU using a single variable, the area under the curve of ROC from Delta Q (0.806) was significantly higher than that from Qmax (0.763, p=0.0126) and Qave (0.574, p<0.0001).
Conclusion: Our findings suggest that Delta Q is a novel predictor capable of discriminating DU from BOO in men with obstructive lower urinary tract symptom.

목차

Introduction 1
Materials and Methods 3
Results 6
Discussion 10
Conclusions 13
References 14
Korean abstract 17

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