지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학위논문
- 저자정보
- 지도교수
- 임윤경
- 발행연도
- 2013
- 저작권
- 대전대학교 논문은 저작권에 의해 보호받습니다.
이용수0
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Objective :
The purpose of this study is evaluating the effect of Hoelen Herbal-acupuncture(HO-HA) at KI10(Umgok) on LPS(Lipopolysaccharide) induced nephritis in rats
Methods :
The experimental rats were assigned to four groups; normal, LPS, saline, HO-HA groups. LPS (2㎎/㎏) was administered to the rats in LPS, saline and HO-HA groups to induce acute inflammatory kidney damage. Saline injection and HO-HA were administered at KI10 three times a week.
Blood samples were taken from the rats for analysis of WBC, neutrophil, BUN, creatinine TNF-α, CINC-1. Urine samples were taken from the rats for analysis of urinal volume, creatinine and total protein. The kidney samples were taken from the rats for analysis of renal MPO.
Results :
HO-HA suppressed the increases of WBC and neutrophils in blood, BUN, creatinine, TNF-α and CINC-1 in serum, and MPO in kidney of LPS-stimulated rats. In addition, HO-HA inhibited the decrease of urinary volume in LPS-stimulated rats.
Conclusion :
HO-HA has therapeutic effects on LPS-induced inflammatory kidney damage in rats. Further studies may be needed for clinical use of HO-HA.
The purpose of this study is evaluating the effect of Hoelen Herbal-acupuncture(HO-HA) at KI10(Umgok) on LPS(Lipopolysaccharide) induced nephritis in rats
Methods :
The experimental rats were assigned to four groups; normal, LPS, saline, HO-HA groups. LPS (2㎎/㎏) was administered to the rats in LPS, saline and HO-HA groups to induce acute inflammatory kidney damage. Saline injection and HO-HA were administered at KI10 three times a week.
Blood samples were taken from the rats for analysis of WBC, neutrophil, BUN, creatinine TNF-α, CINC-1. Urine samples were taken from the rats for analysis of urinal volume, creatinine and total protein. The kidney samples were taken from the rats for analysis of renal MPO.
Results :
HO-HA suppressed the increases of WBC and neutrophils in blood, BUN, creatinine, TNF-α and CINC-1 in serum, and MPO in kidney of LPS-stimulated rats. In addition, HO-HA inhibited the decrease of urinary volume in LPS-stimulated rats.
Conclusion :
HO-HA has therapeutic effects on LPS-induced inflammatory kidney damage in rats. Further studies may be needed for clinical use of HO-HA.
목차
Ⅰ. 서 론 1Ⅱ. 실 험 31. 재 료 31) 동 물 32) 약재 33) 시약 및 기기 4(1) 시약 4(2) 기기 42. 방 법 51) 약침액의 제조 52) 염증성 신 손상 동물 모델 73) 실험군 분류 및 처치 74) 결과 분석 8(1) 혈액 분석 8(2) 소변 분석 8(3) 신장 내 염증활성 평가 8(4) 통계분석 8Ⅲ. 성 적 101. LPS투여에 따른 TNF-α의 농도 변화 101) Serum TNF-α 102) Renal TNF-α 112. 음곡 백복령 약침이 LPS에 의한 rat의 염증성 신 손상에 미치는 영향 121) 혈액학적 분석 12(1) WBC 13(2) Neutrophil 142) Blood chemistry 15(1) BUN 16(2) Creatinine 17(3) TNF-α 18(4) CINC-1 193) 소변 분석 20(1) 이뇨 활성 21(2) Creatinine 22(3) Total protein 234) 신장 내 염증활성 24(1) MPO 25Ⅳ. 고 찰 26Ⅴ. 결 론 32참고문헌 33ABSTRACT 36
최근 본 자료
댓글(0)
0