Objectives This Study aims to examine differences in the hepatic function disorders and prevalence rates of liver diseases in accordance with the Sasang constitutional type, and to analyze whether Sasang constitutions is significant as a risk factor for fatty liver.
Methods 1,211 patients who underwent health check-up at the Ilsan Hospital of Dongguk University and had their physical constitutions diagnosed by a specialist in Sasang constitutional medicine from October 31, 2011 to September 28, 2012 were used as the subjects of this Study. Presence of hepatobiliary diseases was analyzed from the results of the hepatic function test, lipid test and viral hepatitis infection marker test in the biochemistry tests, and abdominal ultrasonography.
Results & Conclusions 1. The subjects of the Study was composed of 691 males (57.1%) and 520 females (42.9%), and, in terms of Sasang constitution distribution, 550 Taeeumin (45.4%), 343 Soeumin (28.3%) and 318 Soyangin (26.3%).
2. As the result of analysis of prevalence rate in accordance with gender, male displayed statistically significantly higher rate of belonging to the abnormal groups of the AST, ALT, GGT, Total bilirubin, Albumin, Total cholesterol, Triglyceride, HDL-cholesterol in comparison to female, and, as the result of abdominal ultrasonography, the prevalent rates of fatty liver and polyps of gallbladder were significantly higher in male.
3. As the results of analysis of prevalence rates in accordance with Sasang constitutions, significant differences were observed in the prevalence rates of abnormal groups in the cases of AST, ALT, GGT, Triglyceride, HDL-cholesterol and LDL-cholesterol, and the all of their prevalence rates were in the descending order of Taeeumin, Soyangin and Soeumin. Soeumin displayed significantly higher positive rate for HBs Ab in comparison to the Taeeumin and Soyangin. In the results of abdominal ultrasonography, the prevalence rates of fatty liver displayed significant differences and were in the descending order of Taeeumin, Soyangin and Soeumin.
4. Prevalence rates of fatty liver were analyzed in accordance with the gender and Sasang constitutions by categorizing them in to Grades 1, 2 and 3 according to their severity. In the case of gender comparison, prevalence rates were significantly higher in male than in female for the Grades 1 & 2. In the case of comparison for each of the Sasang constitutions, prevalence rates was found to be in the descending order of Taeeumin, Soyangin and Soeumin for the Grades 1 & 2, and all displayed significant differences between each of the physical constitutions. Grade 3 fatty liver corresponded to all male and to Taeeumin.
5. As the results of execution of logistics regression analysis with the gender, age, BMI, bio-chemical test results along with the Sasang constitutions as the independent variable, and presence of fatty liver as the dependent variable in order to find the risk factors of fatty liver, the Sasang constitutions was found to be a significant risk factor for fatty liver. The extent of risk of fatty liver in Taeeumin was found to be 1.634 times higher than Soeumin and 1.773 times higher than Soyangin.
Ⅰ. 緖論 = 01Ⅱ. 方法 = 031. 연구 대상 = 032. 연구방법 = 031) 사상체질 진단 = 032) 생화학검사 = 033) 신체계측 = 044) 복부초음파 = 043. 통계분석 = 05Ⅲ. 結果 = 061. 연구대상자들의 일반적 특성 = 062. 체질별 BMI 비교 = 083. 생화학 검사 비정상군의 유병률 분석 = 091) 성별 생화학 검사 비정상군의 유병률 분석 = 092) 체질별 생화학 검사 비정상군의 유병률 분석 = 114. 바이러스성 간염 항체 및 항원의 양성률 분석 = 131) 성별 항체 및 항원의 양성률 분석 = 132) 체질별 항체 및 항원의 양성률 분석 = 145. 복부초음파에서 간담질환의 유병률 분석 = 151) 성별 간담질환 유병률 분석 = 152) 체질별 간담질환 유병률 분석 = 176. 지방간 등급별 유병률 분석 = 201) 성별 지방간의 심한 정도에 대한 유병률 분석 = 202) 체질별 지방간의 심한 정도에 대한 유병률 분석 = 227. 지방간의 위험요인 = 248. 체질별 지방간의 비교위험도 = 26Ⅳ. 考察 = 27Ⅴ. 結論 = 37參考文獻 = 39<참고자료> 태양인의 간기능 이상 및 초음파 상의 간담질환 = 42