지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학위논문
- 저자정보
- 지도교수
- 윤상협
- 발행연도
- 2013
- 저작권
- 경희대학교 논문은 저작권에 의해 보호받습니다.
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초록· 키워드
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Objectives : The aims of this study is to found out whether Jichul-hwan(JCH) extract have an effect on gastric contractility in conscious rats by using force transducer implanted in the body of stomach.
Methods : The force transducer(model: F-081S, Starmedical, JAPAN) was implanted to the exterior wall of the stomach body in rats. The gastric contractility was measured 30 minutes before and after administration of JCH (110.1mg/kg). And, the control group was administrated with normal saline instead of JCH to compare the effect of JCH. The gastric contractility of control group(Normal Saline:NS) was also measured 30 minutes before and after administration of NS.
Results : The ratio of gastric contractility between before and after medication by JCH was 1.707±0.731, and with NS was 0.701±0.541. The gastric motility increased by JCH was significantly higher than NS.
Conclusions : JCH extract increases gastric contractility in conscious rats. We could expect that this drug would be effective in the treatment of functional dyspepsia or post-surgical gastroparesis.
Methods : The force transducer(model: F-081S, Starmedical, JAPAN) was implanted to the exterior wall of the stomach body in rats. The gastric contractility was measured 30 minutes before and after administration of JCH (110.1mg/kg). And, the control group was administrated with normal saline instead of JCH to compare the effect of JCH. The gastric contractility of control group(Normal Saline:NS) was also measured 30 minutes before and after administration of NS.
Results : The ratio of gastric contractility between before and after medication by JCH was 1.707±0.731, and with NS was 0.701±0.541. The gastric motility increased by JCH was significantly higher than NS.
Conclusions : JCH extract increases gastric contractility in conscious rats. We could expect that this drug would be effective in the treatment of functional dyspepsia or post-surgical gastroparesis.
목차
Ⅰ. 緖 論 1Ⅱ. 實 驗 21. 재료 21) 동물 22) 약물 23) Force transducer 22. 방법 41) 실험 protocol 42) Operation 43) 위 수축력 측정 43. 통계처리 8Ⅲ. 結 果 9Ⅳ. 考 察 12Ⅴ. 結 論 14參 考 文 獻 15ABSTRACT 17
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