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논문 기본 정보

자료유형
학술저널
저자정보
김탁돈 (충남대학교) 이희영 (인제대학교)
저널정보
한국임상약학회 한국임상약학회지 한국임상약학회지 제34권 제3호
발행연도
2024.9
수록면
141 - 154 (14page)
DOI
10.24304/kjcp.2024.34.3.141

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초록· 키워드

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Background: As preexisting comorbidities are risk factors for Coronavirus Disease 19 (COVID-19), improved tools are needed for screening or diagnosing COVID-19 in clinical practice. Difficulties of including vulnerable patient data may create data im balance and hinder the provision of well-performing prediction tools, such as artificial intelligence (AI) models. Thus, we system atically reviewed studies on AI prognosis prediction in patients infected with COVID-19 and existing comorbidities, including cancer, to investigate model performance and predictors dependent on patient data. PubMed and Cochrane Library databases were searched. This study included research meeting the criteria of using AI to predict outcomes in COVID-19 patients, whether they had cancer or not. Preprints, abstracts, reviews, and animal studies were excluded from the analysis. Majority of non-cancer studies (54.55 percent) showed an area under the curve (AUC) of >0.90 for AI models, whereas 30.77 percent of cancer studies showed the same result. For predicting mortality (3.85 percent), severity (8.33 percent), and hospitalization (14.29 percent), only cancer studies showed AUC values between 0.50 and 0.69. The distribution of comorbidity data varied more in non-cancer stud ies than in cancer studies but age was indicated as the primary predictor in all studies. Non-cancer studies with more balanced datasets of comorbidities showed higher AUC values than cancer studies. Based on the current findings, dataset balancing is es sential for improving AI performance in predicting COVID-19 in patients with comorbidities, especially considering age.

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