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논문 기본 정보

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학술저널
저자정보
Yun Jeong-Eun (Division of Allergy and Clinical Immunology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.) Ko Eun Byeol (Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea) Jung Hae In (Division of Pulmonary and Allergy Medicine, Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medi) Gu Kang-Mo (Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.) Kim Tae Wan (Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.) Park So-Young (Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Division of Pulmonary, Allergy and Critical Care Medicine, Chung-Ang University Gwangmyeong Hospital,) Baek Moon Seong (Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.) Kim Won-Young (Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.) Choi Jae Chol (Division of Pulmonary, Allergy and Critical Care medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea.Department of Internal Medicine, Chung-Ang University College of Medi) Shin Jong-Wook (Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.) Kim Jae Yeol (Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.) Chang Young D. (Department of Internal Medicine, Tampa General Hospital, Tampa, FL, USA.Department of Internal Medicine, University of South Florida, Tampa, FL, USA) Jung Jae-Woo (Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.)
저널정보
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research AAIR Vol.16 No.5
발행연도
2024.9
수록면
534 - 545 (12page)
DOI
10.4168/aair.2024.16.5.534

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Purpose: Allergen exposure is the most potent factor in allergen sensitization, which affects the exacerbation and severity of allergic diseases. Due to industrialization and climate change, the pattern of allergen sensitization has changed over time, and the incidence of allergic diseases has also increased. This study investigated the status of allergen sensitization in the Korean population and its effects on allergic diseases. Methods: A total of 2,386 participants aged ≥ 10 years, who underwent 7 specific immunoglobulin E tests for aeroallergens (Dermatophagoides farinae [Der f], dog dander, cat epithelium, birch, oak, Japanese hop, and ragweed), were selected among the participants of the 2019 Korean National Health and Nutrition Examination Survey. We compared the demographic characteristics, combined allergic diseases, and sinusitis symptoms between the atopic and non-atopic groups. Results: The prevalence of allergen sensitization in the general Korean population was 45%, and Der f was the most frequent cause of sensitization (39.9%). The prevalence of sensitization to indoor allergens was highest among teenagers and those belonging to the 20- to 29-year age group (P < 0.001). In contrast, there was a high prevalence of sensitization to outdoor allergens among individuals belonging to the age group of 60–69 years. The prevalence of atopic dermatitis (odds ratio [OR], 2.559; 95% confidence interval [CI], 1.689–3.878), allergic rhinitis (OR, 3.075; 95% CI, 2.426–3.897), and otitis media (OR, 1.481; 95% CI, 1.092–2.007) significantly increased by allergen sensitization. Patients with allergen sensitization were more likely to experience the symptoms of rhinitis and sinusitis. Conclusions: The study findings confirmed that allergen sensitization occurs in approximately half of the general Korean population and affects the prevalence and symptoms of allergic diseases. This suggests that active allergy tests and diagnosis of allergic diseases are necessary in Koreans.
#Hypersensitivity #allergens #allergic rhinitis #Korea #population #health care surveys

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