지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.7
- 수록면
- 388 - 393 (6page)
- DOI
- https://doi.org/10.3342/kjorl-hns.2023.00661
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초록· 키워드
오류제보하기
Background and Objectives Chronic rhinosinusitis with nasal polyposis (CRSwNP) is onephenotype of the diffuse type. In spite of surgical and medical treatment, the polyp recurrencerate is high. Recently biologics are concerned as a therapeutic option of it. To figure out ad-verse events associated with the dupilumab injection in adult patients with CRSwNP.
Subjects and Method Retrospective chart review of patients that were treated with dupil-umab from January 2022 to December 2022 for CRSwNP was performed.
Results Of 40 patients (23 of male and 17 of female), 8 patients (20.0%) experienced 9 pa-tients (22.5%) adverse events. The most common adverse event was skin reaction (3 patients,7.5%), followed by 2 of pruritis, 2 of epistaxis. Three patients quit dupilumab after the adverseevents, 4 patients continued, and 1 patient hold the next injection.
Conclusion Dupilumab is reported to be relatively safe medication. However, physicianshould notice that adverse events including skin rash can occur after dupilumab injection.
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