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논문 기본 정보

자료유형
학술저널
저자정보
Ryu Dong-Woo (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Lee ChungHwee (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Lee Hyuk-je (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Shim Yong S (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Hong Yun Jeong (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Cho Jung Hee (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.) Kim Seonggyu (Department of Electronic Engineering, Hanyang University, Seoul, Korea.) Lee Jong-Min (Department of Biomedical Engineering, Hanyang University, Seoul, Korea.) Yang Dong Won (Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.)
저널정보
대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제23권 제3호
발행연도
2024.7
수록면
127 - 135 (9page)
DOI
10.12779/dnd.2024.23.3.127

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Background and Purpose: To ensure data privacy, the development of defacing processes, which anonymize brain images by obscuring facial features, is crucial. However, the impact of these defacing methods on brain imaging analysis poses significant concern. This study aimed to evaluate the reliability of three different defacing methods in automated brain volumetry. Methods: Magnetic resonance imaging with three-dimensional T1 sequences was performed on ten patients diagnosed with subjective cognitive decline. Defacing was executed using mri_deface, BioImage Suite Web-based defacing, and Defacer. Brain volumes were measured employing the QBraVo program and FreeSurfer, assessing intraclass correlation coefficient (ICC) and the mean differences in brain volume measurements between the original and defaced images. Results: The mean age of the patients was 71.10±6.17 years, with 4 (40.0%) being male. The total intracranial volume, total brain volume, and ventricle volume exhibited high ICCs across the three defacing methods and 2 volumetry analyses. All regional brain volumes showed high ICCs with all three defacing methods. Despite variations among some brain regions, no significant mean differences in regional brain volume were observed between the original and defaced images across all regions. Conclusions: The three defacing algorithms evaluated did not significantly affect the results of image analysis for the entire brain or specific cerebral regions. These findings suggest that these algorithms can serve as robust methods for defacing in neuroimaging analysis, thereby supporting data anonymization without compromising the integrity of brain volume measurements.

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