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논문 기본 정보

자료유형
학술저널
저자정보
Kentaro Imamura (Department of Endoscopy, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Kenshi Yao (Department of Endoscopy, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Satoshi Nimura (Department of Pathology, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Takao Kanemitsu (Department of Endoscopy, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Masaki Miyaoka (Department of Endoscopy, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Yoichiro Ono (Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Toshiharu Ueki (Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan) Hiroshi Tanabe (Department of Pathology, Fukuoka University Chikushi Hospital, Fukuoka, Japan)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy Vol.57 No.4
발행연도
2024.7
수록면
486 - 494 (9page)
DOI
10.5946/ce.2023.258

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초록· 키워드

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Background/Aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC.Methods: This single-center retrospective study selected participants from patients with gastric cancer who were treated at the Fukuoka University Chikushi Hospital between January 2013 and December 2021. Only patients diagnosed with HPNGC were enrolled, and their clinicopathological and endoscopic features were analyzed in detail.Results: The prevalence of HPNGC in the present study was 2.6% (54/2,112). The types of HPNGC observed in each gastric region were as follows: advanced gastric cancer was observed in the cardia; gastric adenocarcinoma of fundic-gland differentiation, gastric adenocarcinoma of foveolar-type presenting with whitish elevation and raspberry-like foveolar-type gastric adenocarcinoma, gastric adenocarcinoma arising in polyposis, and gastric adenocarcinoma with autoimmune gastritis were observed in the fundic gland region ranging from the gastric fornix to the gastric body; signet-ring cell carcinoma was observed in the gastric-pyloric transition region ranging from the lower gastric body to the gastric angle; and well-differentiated tubular adenocarcinoma with low-grade atypia was observed in the antrum.Conclusions: This study revealed that tumors from each gastric region exhibited distinct macroscopic and histological types in HPNGC.

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