지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.12
- 수록면
- 309 - 315 (7page)
- DOI
- 10.20307/nps.2024.30.4.309
이용수
초록· 키워드
오류제보하기
Cuscutae Semen has a long-standing history as a traditional herbal medicine widely utilized in East Asian countries, including Korea, China, Hong Kong, and Taiwan. The Korean Herbal Pharmacopoeia (KHP) exclusively recognizes Cuscuta chinensis Lam. as the authentic source of Cuscutae Semen, whereas other countries also accept Cuscuta australis R.Br. This discrepancy has resulted in imports containing both species, which contravenes local regulations. Furthermore, a significant portion of domestically produced Cuscutae Semen is actually Cuscuta japonica Chois., regarded as an adulterant, which further complicates the market. This situation underscores the urgent need for clear differentiation of the botanical origins of Cuscutae Semen. In this study, a high-performance thin-layer chromatography (HPTLC) method was developed to simultaneously differentiate the three origins of Cuscutae Semen: C. chinensis, C. australis, and C. japonica. By utilizing a TLC scanner and TLC-MS interface, the chemical fingerprints of the samples were analyzed in detail. The results revealed that while C. chinensis and C. australis share similar profiles, they can be distinguished by the presence or absence of astragalin and kaempferol. In contrast, C. japonica showed distinct differences, characterized by the presence of chlorogenic acid derivatives. This method demonstrated the ability to rapidly and accurately differentiate between Cuscutae Semen origins, making it a cost-effective and reliable tool for ensuring quality control. It is expected to contribute to improving the standardization and reliability of herbal medicine quality management in the domestic market.
목차
Abstract
Introduction
Experimental
Results and Discussion
References
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