지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.5
- 수록면
- 1 - 9 (9page)
- DOI
- https://doi.org/10.3802/jgo.2024.35.e35
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초록· 키워드
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Objective: To develop and validate a novel scoring system for predicting the risk of uterineperforation during brachytherapy (BT) in cer vical cancer patients and to stratif y patientsbased on this score to guide the use of ultrasound guidance during BT.
Methods: Fifty patients with uterine perforation during BT between Januar y 2018 andDecember 2020 were included. Common reasons for perforation were identified and ascoring system was developed. This was then applied to a cohort of 50 patients withoutperforation. The 2 cohorts were compared using the χ2 test. To validate the scoring system, allnewly diagnosed patients who under went BT in 2021 were scored, and analysed using χ2 testand receiver operator characteristic cur ves.
Results: The mean score in the test cohort was 10.16 (range=7–14) and 5.92 (range=5–8)for patients with and without perforation. In the validation cohort, the mean score was 6.9(range=5–10) and 9.33 (range=7–11) for those with and without perforation. Patients witha score <8 were classified as low risk, while those with a score ≥8 were classified as highrisk. Among the criteria evaluated for validation, response to external beam radiotherapy,uterine position, cer vico-uterine angle (uterine flexion), identification of cer vical os atBT assessment, and the total score were significant predictors, while previous histor y ofperforation, uterine length, and additional uterine anomaly were not.
Conclusion: The novel scoring system is an effective predictor of perforation risk during BT.
Implementing this during BT assessment can optimize the need for ultrasound guidanceduring the procedure.
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