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논문 기본 정보

자료유형
학술저널
저자정보
Seung-Hyuk Shim (Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine) Jiwon Lim (Division of Cancer Registration and Surveillance, National Cancer Center, Goyang, Korea) 김지현 (국립암센터) Yeon Jee Lee (Research Institute and Hospital, National Cancer Center, Goyang, Korea) Hyeong In Ha (Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Korea) 임명철 (국립암센터) 원영주 (연세대학교)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.35 No.3
발행연도
2024.5
수록면
1 - 11 (11page)
DOI
https://doi.org/10.3802/jgo.2024.35.e32

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Objective: To evaluate trends in the incidence and sur vival outcomes of endometrial cancer(EC) based on the year of diagnosis, stage, age, and histologic types. Methods: Women with primar y EC diagnosed between 1999 and 2018, and who werefollowed up with until 2019, were identified from the Korea Central Cancer Registr y usingthe International Classification of Diseases, 10th revision. The age-standardized rates (ASRs)of incidence, annual percent changes (APCs), and sur vival were estimated according to age,stage, histology, and year of diagnosis. Results: The ASR for EC increased from 2.38 per 100,000 in 1999 to 7.29 per 100,000 in2018 across all histologic types (APCs of 9.82, 15.97, and 7.73 for endometrioid, serous, andclear cell, respectively, p<0.001). There were significant differences in the 5-year sur vivalrates based on histology (90.9%, 55.0%, and 68.5% for endometrioid, serous, and clear cell,respectively, p<0.001), stage (93.4%, 77.0%, and 31.0% for localized, regional, and distant,respectively, p<0.001), and age (93.0% for <50 years and 80.6% for ≥50 years, p<0.001). The 5-year sur vival was significantly better in the group diagnosed between 2000 and 2018(85.9%) than that in the 1999–2008 group (83.3%) (p<0.001). This trend was only obser vedfor endometrioid cancer (p<0.001). Conclusion: The incidence of EC increased across the all 3 subtypes. Sur vival of patients withendometrioid histology improved over the past two decades, but remained static for serousor clear cell histology. Healthcare strategies to prevent EC incidence in at-risk populationsand apply effective treatments for high-risk histology are needed.

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