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논문 기본 정보

자료유형
학술저널
저자정보
Han Du-Gyeong (Department of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Infectious Disease, Korea National Institute of Health, Korea Disease Control and Prev) Jeong Ji-A (Department of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Infectious Disease, Korea National Institute of Health, Korea Disease Control and Prev) Lee Sung-Kyoung (Department of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Infectious Disease, Korea National Institute of Health, Korea Disease Control and Prev) Kim Seong-Han (Department of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Infectious Disease, Korea National Institute of Health, Korea Disease Control and Prev) Jeon Se-Mi (Department of Bacterial Disease Research, Center for Infectious Disease Research, National Institute of Infectious Disease, Korea National Institute of Health, Korea Disease Control and Prev)
저널정보
한국미생물생명공학회 한국미생물·생명공학회지 한국미생물·생명공학회지 제52권 제2호
발행연도
2024.6
수록면
211 - 214 (4page)
DOI
10.48022/mbl.2403.03005

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초록· 키워드

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This study aimed to confirm the induction of resistance to other drug classes by treating Mycobacterium abscessus with moxifloxacin, a fluoroquinolone used for treating nontuberculous mycobacteria infection, and to obtain genetic data for improving treatment. The reads were assembled and analyzed using reference strain sequence data, and the whole-genome and transcriptome sequences of four strains (MD2, MD4, MD6, and MD8) were reported. Antibiotic resistance was not induced by moxifloxacin treatment; however, transcriptomic analysis revealed that the expression of genes responding to stress was upregulated.

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