지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한백신학회 Clinical and Experimental Vaccine Research Clinical and Experimental Vaccine Research Vol.13 No.1
- 발행연도
- 2024.1
- 수록면
- 42 - 53 (12page)
- DOI
- 10.7774/cevr.2024.13.1.42
이용수
초록· 키워드
오류제보하기
Purpose: Conduct a systematic review of case reports and case series regarding the de velopment of acute abdomen following coronavirus disease 2019 (COVID-19) vaccination, to describe the possible association and the clinical and demographic characteristics in detail.
Materials and Methods: This study included case report studies and case series that fo cused on the development of acute abdomen following COVID-19 vaccination. Systematic review studies, literature, letters to the editor, brief comments, and so forth were excluded.
PubMed, Scopus, EMBASE, and Web of Science databases were searched until June 15, 2023. The Joanna Briggs Institute tool was used to assess the risk of bias and the quality of the study. Descriptive data were presented as frequency, median, mean, and standard deviation.
Results: Seventeen clinical case studies were identified, evaluating 17 patients with acute ab domen associated with COVID-19 vaccination, which included acute appendicitis (n=3), acute pancreatitis (n=9), diverticulitis (n=1), cholecystitis (n=2), and colitis (n=2). The COVID-19 vaccine most commonly linked to acute abdomen was Pfizer-BioNTech (messenger RNA), ac counting for 64.71% of cases. Acute abdomen predominantly occurred after the first vaccine dose (52.94%). All patients responded objectively to medical (88.34%) and surgical (11.76%) treatment and were discharged within a few weeks. No cases of death were reported.
Conclusion: Acute abdomen is a rare complication of great interest in the medical and surgi cal practice of COVID-19 vaccination. Our study is based on a small sample of patients; there fore, it is recommended to conduct future observational studies to fully elucidate the underly ing mechanisms of this association.
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