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논문 기본 정보

자료유형
학술저널
저자정보
Shintaro Togashi (Center for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Wako-shi, Japan) Hironori Ohinata (Faculty of Health Sciences, Hokkaido University, Sapporo, Japan) Taiji Noguchi (Department of Social Science, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan) Hidetaka Wakabayashi (Department of Rehabilitation Medicine, Tokyo Women’s Medical University Hospital, Shinjuku, Japan) Mariko Nakamichi (Department of Pharmacy, Haradoi Hospital, Fukuoka, Japan) Akio Shimizu (Department of Food and Health, Faculty of Health and Human Development, The University of Nagano, Nagano, Japan) Shinta Nishioka (Department of Clinical Nutrition and Food Service, Nagasaki Rehabilitation Hospital, Nagasaki, Japan) Ryo Momosaki (Department of Rehabilitation Medicine, Mie University Graduate School of Medicine, Tsu, Japan)
저널정보
대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.28 No.1
발행연도
2024.3
수록면
86 - 94 (9page)
DOI
10.4235/agmr.23.0203

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Background: Although the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged ≥65 years with dysphagia. Methods: In this 19‐center cohort study, we registered 467 inpatients aged ≥65 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores ≤8 between November 2019 and March 2021. Polypharmacy was defined as prescribing ≥5 medications and PIMs were identified based on the 2023 Updated Beers Criteria. We applied a generalized linear regression model to examine the association of polypharmacy and PIMs with FILS score at discharge. Results: We analyzed 399 participants (median age, 83.0 years; males, 49.8%). The median follow‐up was 51.0 days (interquartile range, 22.0–84.0 days). Polypharmacy and PIMs were present in 67.7% of and 56.1% of patients, respectively. After adjusting for covariates, neither polypharmacy (β = 0.05; 95% confidence interval [CI], -0.04–0.13, p=0.30) nor non‐steroidal anti‐inflammatory medications (β = 0.09; 95% CI, -0.02–0.19; p=0.10) were significantly associated with FILS score at discharge. Conclusions: The results of this study indicated a high proportion of polypharmacy and PIMs among inpatients aged ≥65 years with dysphagia. Although these prescribed conditions were not significantly associated with swallowing function at discharge, our findings suggest the importance of regularly reviewing medications to ensure the appropriateness of prescriptions when managing older inpatients.

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