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논문 기본 정보

자료유형
학술저널
저자정보
Alex Barnes (Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre) Jane M Andrews (Inflammatory Bowel Disease Service, Department of Gastroenterology and Hepatology, Central Adelaide Local Health Network (CALHN) Royal Adelaide Hospital) Sutapa Mukherjee (Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University) Robert V Bryant (School of Medicine, Faculty of Health & Medical Sciences, University of Adelaide) Peter Bampton (Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University) Robert J. Fraser (Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre) Réme Mountifield (Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.22 No.1
발행연도
2024.1
수록면
104 - 114 (11page)
DOI
10.5217/ir.2023.00028

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Background/Aims: Insomnia is common in people with chronic medical conditions, such as inflammatory bowel disease (IBD), and is readily treatable through cognitive behavioral therapy for insomnia. This study aimed to describe the associations with insomnia in people with IBD and its relationship to IBD-related disability.Methods: An online questionnaire was administered through 3 tertiary IBD centers, social media, and Crohn’s Colitis Australia. The questionnaire included the Insomnia Severity Index (ISI), a validated assessment of insomnia. Measures of anxiety, depression, physical activity, and disability were also included. IBD activity was assessed using validated patient reported scores. A multivariate model was constructed for clinically significant insomnia and ISI scores. Subpopulations of Crohn’s disease and ulcerative colitis were considered.Results: In a cohort of 670 respondents the median age was 41 years (range, 32–70 years), with the majority female (78.4%), the majority had Crohn’s disease (57.3%). Increasingly severe disability was associated with worse insomnia score. Clinically significant insomnia was associated with clinically active IBD, abdominal pain, anxiety, and depression, in a multivariate model. In an ulcerative colitis population, Simple Clinical Colitis Activity Index components of general well-being and urgency were associated with worse ISI score in a model including depression and anxiety. In those with Crohn’s disease, the multivariate model included Harvey Bradshaw Index score in addition to depression and anxiety.Conclusions: Insomnia is common in people with IBD and is associated with increased disability. Abdominal pain and mental health conditions should prompt consideration for screening for insomnia and referral for cognitive behavioral therapy for insomnia.

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