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Primary leiomyosarcoma of the bone: a case report
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논문 기본 정보

Type
Academic journal
Author
Ala Abu-Dayeh (Hamad Medical Corporation) Samir Alhyassat (Hamad Medical Corporation)
Journal
대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine Vol.58 No.1 KCI Accredited Journals
Published
2024.1
Pages
35 - 39 (5page)
DOI
10.4132/jptm.2023.11.14

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Primary leiomyosarcoma of the bone: a case report
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Primary leiomyosarcoma of the bone is rare. Histologically, it resembles leiomyosarcoma of soft tissue. Given the rarity of this entity, its diagnosis should be made only after clinical studies and workup have excluded metastasis from other sites. Herein, we describe an additional case of primary bone leiomyosarcoma. We report a 32-year-old female patient, who presented with right knee pain and was found to have a right distal femur mass by imaging studies. Biopsy showed a neoplasm composed of fascicles of spindle cells, arranged in different patterns, with significant pleomorphism. The tumor cells were positive for smooth muscle actin, focally positive for desmin and H-caldesmon. No other masses in the body were detected by imaging studies. The diagnosis of leiomyosarcoma of the bone was rendered. Given the broad diagnostic differential of primary bone leiomyosarcoma, it is important to be aware of this rare bone tumor phenotype and of its histomorphologic and immunohistochemical features for an accurate diagnosis.
#Bone #Sarcoma #Leiomyosarcoma #Case report

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