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논문 기본 정보

자료유형
학술저널
저자정보
Lee Juyeon (Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Korea.D) Choo Chang-Woo (Seoul Maria Fertility Hospital, Seoul, Korea.) Moon Kyoung Yong (Seoul Maria Fertility Hospital, Seoul, Korea.) Lyu Sang Woo (P&S Fertility Center, Seoul, Korea) Kim Hoon (Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea) Lee Joong Yeup (Hamchoon Women’s Clinic, Seoul, Korea.) Lee Jung Ryeol (Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seon) Jee Byung Chul (Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seon) Hwang Kyungjoo (Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.) Kim Seok Hyun (Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.) Park Sue K. (Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.Department Cancer Institution, Seoul National University, Seoul, Korea.Integrated Major in Inno)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.39 No.10
발행연도
2024.3
수록면
1 - 11 (11page)
DOI
10.3346/jkms.2024.39.e85

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초록· 키워드

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Background: Female infertility is a crucial problem with significant implications for individuals and society. In this study, we explore risk factors for infertility in Korean women. Methods: A total of 986 female patients who visited six major infertility clinics in Korea were recruited from April to December 2014. Fertile age-matched controls were selected from two nationwide survey study participants. Conditional logistic regression after age-matching was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) of each risk factor for infertility. Results: Women with a body mass index (BMI) < 18.5 kg/m2 had 1.35 times higher odds of infertility (OR, 1.35; 95% CI, 1.03–1.77), while those with a BMI ≥ 25.0 kg/m2 had even higher odds (OR, 2.06; 95% CI, 1.61–2.64) compared to women with a normal BMI (18.5 kg/m2 ≤ BMI < 25 kg/m2 ). Ever-smokers exhibited 4.94 times higher odds of infertility compared to never-smokers (95% CI, 3.45–8.85). Concerning alcohol consumption, women who consumed ≥ 7 glasses at a time showed 3.13 times significantly higher odds of infertility than those who consumed ≤ 4 glasses at a time (95% CI, 1.79–5.48). Lastly, women with thyroid disease demonstrated 1.44 times higher odds of infertility compared to women without thyroid disease (95% CI, 1.00–2.08). Conclusion: Female infertility in Korea was associated with underweight, obesity, smoking, alcohol consumption, and thyroid disease.

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