지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 18 - 26 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: Studies on the appropriate amount of anti-adhesive agents for preventing postoperative adhesion are lacking. This animal study aimed to investigate the distribution of an anti-adhesive agent in the abdominal cavity and estimate the necessary amount to cover the entire cavity.
Methods: Fluorescent dye Flamma-552 was conjugated to Guardix-sol to create Guardix-Flamma, which was laparoscopically applied to the abdominal cavity of two 10-kg pigs in different amounts: 15 mL for G1 and 35 mL for G2. After 24 hours, the distribution of Guardix-Flamma was examined under the near-infrared mode of the laparoscope, and the thickness was measured in tissues from the omentum, small, and large intestine by immunohistochemistry.
Results: The average area of the abdominal cavity in 10 kg pigs was 2,755 cm2. Guardix-Flamma fluorescence was detected in the greater omentum, ascites in the pelvis, and right quadrant area in G1, whereas in G2, it was detected everywhere. On average, the total thickness of G1 and G2 were 12.68±9.80 μm and 18.16±15.57 μm, respectively. Guardix-Flamma thickness applied to the omentum, small, and large intestines of G2 were 1.31-, 1.45-, and 1.49-times thicker than those of G1, respectively, and were all statistically significant (P<0.05).
Conclusion: The entire abdominal cavity of the 10 kg pig was not evenly covered with 15 mL of Guardix. Although 35 mL of Guardix is sufficient to cover the same area with an average thickness of 18 μm, further studies should evaluate the minimum thickness required for an effective anti-adhesive function.
Methods: Fluorescent dye Flamma-552 was conjugated to Guardix-sol to create Guardix-Flamma, which was laparoscopically applied to the abdominal cavity of two 10-kg pigs in different amounts: 15 mL for G1 and 35 mL for G2. After 24 hours, the distribution of Guardix-Flamma was examined under the near-infrared mode of the laparoscope, and the thickness was measured in tissues from the omentum, small, and large intestine by immunohistochemistry.
Results: The average area of the abdominal cavity in 10 kg pigs was 2,755 cm2. Guardix-Flamma fluorescence was detected in the greater omentum, ascites in the pelvis, and right quadrant area in G1, whereas in G2, it was detected everywhere. On average, the total thickness of G1 and G2 were 12.68±9.80 μm and 18.16±15.57 μm, respectively. Guardix-Flamma thickness applied to the omentum, small, and large intestines of G2 were 1.31-, 1.45-, and 1.49-times thicker than those of G1, respectively, and were all statistically significant (P<0.05).
Conclusion: The entire abdominal cavity of the 10 kg pig was not evenly covered with 15 mL of Guardix. Although 35 mL of Guardix is sufficient to cover the same area with an average thickness of 18 μm, further studies should evaluate the minimum thickness required for an effective anti-adhesive function.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
족관절 골절 수술에서의 유착방지제(Guardix®)의 효과 연구
대한족부족관절학회지
2017 .12
-
Clinical Results of Anti-adhesion Adjuvants after Endonasal Dacryocystorhinostomy
Korean Journal of Ophthalmology
2018 .01
-
Effects of a Temperature-sensitive, Anti-adhesive Agent on the Clinical Outcome of Carpal Tunnel Release Surgery
Archives of Hand and Microsurgery
2018 .01
-
Effectiveness of the Anti-adhesive Agent Protescal after Arthroscopic Rotator Cuff Repair : A Retrospective Study
대한견주관절의학회지
2017 .03
-
Three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation: Correspondence
Annals of Hepato-Biliary-Pancreatic Surgery
2025 .02
-
Influence of depth of cavity on color blending effect of structurally colored resin
대한치과재료학회지
2023 .12
-
초음파 결합형 압통계를 활용한 압통시 소화불량 환자와 건강인의 복강내 조직 변화 비교: 비무작위 대조군 예비 임상시험
대한예방한의학회지
2023 .04
-
Cost-effective and time-saving three-dimensional (3-D) printing protocol of intra-abdominal cavity of liver transplantation recipient to prevent large-for-size syndrome
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Improved graft survival by using three-dimensional printing of intra-abdominal cavity to prevent large-for-size syndrome in liver transplantation
Annals of Hepato-Biliary-Pancreatic Surgery
2025 .02
-
Measurement of human peritoneal surface area using artificial intelligence software in abdominal computed tomography
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2024 .06
-
Abdominal Mass in Children
대한외과학회 학술대회 초록집
2019 .05
-
Management of an Open Abdomen Considering Trauma and Abdominal Sepsis: A Single-Center Experience
Journal of Acute Care Surgery
2019 .01
-
A Pleural Catheter Malposition through Diaphragm to Abdominal Cavity
Acute and Critical Care
2017 .01
-
비외상성 급성 복부 통증 환자에게 시행한 복부 전산화단층촬 영과 복부 단순 촬영의 적정성 비교
한국의료질향상학회지
2018 .01
-
Case 11: A 31-Year-Old Woman With Abdominal Pain
Journal of Korean Medical Science
2023 .06
-
Erratum : Comparison of Muscle Thickness of Abdominal Muscles According to Various Types of Abdominal Crunch Exercise
대한통합의학회지
2022 .05
-
근관치료의 시작 - 치수강 개방
대한치과의사협회지
2018 .09
-
Abdominal Subcutaneous Fat Thickness Measured by Ultrasonography Correlates with Hyperlipidemia and Steatohepatitis in Obese Children
Pediatric Gastroenterology, Hepatology & Nutrition
2015 .01
-
Traditional and minimally invasive access cavities in endodontics: a literature review
Restorative Dentistry and Endodontics
2021 .08
-
복진(腹診)에 대한 국내 연구동향 분석 및 연구방향 제안
대한한의학회지
2016 .09
최근 본 자료
댓글(0)
0