지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.51 No.2
- 발행연도
- 2024.6
- 수록면
- 159 - 167 (9page)
이용수
초록· 키워드
오류제보하기
Herbal medicinal mushroom Cordyceps militaris has been traditionally used as tonic medicine for metabolic syndrome. Cordycepin, main extract of C. militaris , has been reported with immunomodulatory, anticancer, and hepatoprotective effects. This study was conducted to evaluate the potential hepatoprotective effect of cordycepin-enriched Cordyceps militaris , against high fat diet (HFD)-induced hepatic steatosis (HS) in male obese (ob/ob) mice. HFD was provided to ob/ob mice ad libitum (except negative control). Cordycepin-enriched C. militaris extract powder (CM) was orally administered once daily at dose levels of 0, 125, 250, and 500 mg·kg<SUP>-1</SUP> for 4 weeks. During the study, body weight gain was statistically increased in all HFD fed groups compared to negative control, but body weight gain in CM 500 mg·kg<SUP>-1</SUP> treated group shows a low tendency compared to HS model group. In organ weights, absolute and relative weights (to body weight) in liver and perirenal adipose tissue were increased in all HFD treated groups except CM 500 mg·kg<SUP>-1</SUP> treated group compared to the negative control. In clinical chemistry, serum glucose and total cholesterol levels in CM 250 and/or 500 mg·kg<SUP>-1</SUP> treated groups were lower than HS model group. In microscopical examination, hepatocyte vacuolation with macrovesicles in HS model group was increased compared to negative control, but this finding was decreased in CM 500 mg·kg<SUP>-1</SUP> treated group compared to HS model group. In this study, CM exhibited hepatoprotective effects against hepatic steatosis at mg·kg<SUP>-1</SUP> in ob/ob mice.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Conclusion
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Hepatoprotective Effect of Cordycepin-Enriched Cordyceps militaris Extract Powder on High Fat Diet-Induced Hepatic Steatosis in ob/ob Mice
한국식품영양과학회 학술대회발표집
2018 .10
-
Effect of Quercetin and Deferoxamine on Hepatic Gluconeogenesis and Steatosis and Adipose Tissue Inflammation in High Fat Fed ob/ob Mice
한국식품영양과학회 학술대회발표집
2015 .08
-
Hepatoprotective and Anti-Obesity Properties of Sardine By-Product Oil in Rats Fed a High-Fat Diet
Preventive Nutrition and Food Science
2021 .09
-
Anti-Obesity Effects of Gelidium amansii Extract in the C57BL/6J ob/ob Mice
한국식품영양과학회 학술대회발표집
2015 .08
-
Effects of 3,3"-diindolylmethane on body composition and blood lipid profiles in C57BL/6J ob/ob mice
한국식품영양과학회 학술대회발표집
2015 .08
-
Interventional Multi-Omics Analysis of the Gut-Liver Axis Reveals the Potential Inflammatory Effects of Artificial Sweeteners in the ob/ob Mouse Model
한국식품영양과학회 학술대회발표집
2023 .10
-
Evaluation of liver function using Cordyceps militaris extract powder in Sprague-Dawley rat with acute hepatic injury induced by dimethylnitrosamine
Korean Journal of Agricultural Science
2024 .06
-
Cordycepin Content of Cordyceps militaris by the Media Composition
한국약용작물학회 학술대회논문집
2016 .05
-
Anti-menopausal effect of Cordyceps militaris extract in the ovariectomized mouse model
한국식품영양과학회 학술대회발표집
2024 .10
-
Detection of Trees with Pine Wilt Disease Using Object-based Classification Method
Journal of forest and environmental science
2016 .01
-
HM-chromanone Ameliorates Hyperglycemia via Activating PI3K/AKT Pathway and Improving FOXO1 Pathway in ob/ob Mice
한국식품영양과학회 학술대회발표집
2022 .10
-
Ameliorated effect of Meretrix lusoria Protamex Enzymatic Hydrolysate (ML-Pro) on Hyperglycemia and Obesity disorders in ob/ob mice
한국식품영양과학회 학술대회발표집
2022 .10
-
Anti-hyperglycemic effect of flavorzyme hydrolysate derived from Meretrix lusoria in ob/ob mice
한국식품영양과학회 학술대회발표집
2021 .10
-
Anti-obesity effect of the enzymatic hydrolyzed extract derived from Meretrix lusoria using the animal model (high fat-fed mice or ob/ob mice)
한국식품영양과학회 학술대회발표집
2021 .10
-
Control of Nosema ceranae using Cordyceps militaris media extract in Honeybee
한국양봉학회 학술대회 자료집
2015 .03
-
Improvement Effects of Cordyceps militaris and Cordycepin on Dexamethasone-Induced Muscle Atrophy in Vivo Model
한국식품영양과학회 학술대회발표집
2023 .10
-
Ginger Extract Ameliorates Lipid Accumaulation and Endoplasmic Reticulum Stress of Adipose Tissues by SIRT-1-PGC-1α Signaling via AMPK Activation in ob/ob mice
한국식품영양과학회 학술대회발표집
2022 .10
-
Dietary Isorhamnetin Reduces Obesity-induced Hepatic Steatosis in Mice Fed a High-fat Diet
한국식품영양과학회 학술대회발표집
2018 .10
-
Artemisia annua Leaf Extract Prevents Hepatic Steatosis in High-Fat Diet-fed Mice
한국식품영양과학회 학술대회발표집
2016 .10
-
Cordyceps militaris Protects Hydrogen Peroxide-Induced Oxidative Stress
한국식품영양과학회 학술대회발표집
2018 .10
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-151-24-02-090053217