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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Glucocorticoids (GCs) are steroid hormones regulated through responses to stress to maintain diverse metabolic and homeostatic functions. GCs act on the glucocorticoid receptor (GR), a member of the nuclear receptor family. This study identified and characterized the GR gene from the big-belly seahorse Hippocampus abdominalis designating it HaGR. The open reading frame of the HaGR cDNA was 2,346 bp in length, encoding a 782-amino-acid polypep-tide with a theoretical isoelectric point of 6.26 and predicted molecular mass of 86.8 kDa. Nuclear receptors share a common structural organization, comprising an N-terminal transactivation domain, DNA-binding domain, and C-terminal ligand-binding domain. The tissue-specific mRNA expression profile of HaGR was analyzed in healthy seahorses using a qPCR technique. HaGR mRNA was expressed ubiquitously in all of the tissues examined, with the highest expression levels in kidney, intestine, stomach, and gill tissues. The mRNA expression in response to im-mune challenge with lipopolysaccharide (LPS), polyinosinic:polycytidylic acid (poly I:C), Edwardsiella tarda, and Streptococcus iniae revealed that it is inducible in response to pathogen infection. These results suggest that HaGR is involved in the immune response of the big-belly seahorse.
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Molecular characterization and expression profiling of peptidoglycan recognition protein from big-belly seahorse (Hippocampus abdominalis)
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Characterization and apoptosis based immune responses of B-cell lymphoma-2 family gene from big belly seahorse (Hippocampus abdominalis)
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2016 .05
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Molecular characterization of dim 1 like protein (DLP) from big-belly seahorse (Hippocampus abdominalis) in relevance to immune responses
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Molecular characterization and transcriptional abundance under pathogenic stresses of big-belly seahorse interleukin-10 (Hippocampus abdominalis)
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MOLECULAR IDENTIFICATION AND EXPRESSIONAL ANALYSIS OF A MAJOR PATHOLOGICALLY IMPORTANT KINASE COUNTERPART IRAK4 IN MYD88 DEPENDENT CELL SIGNALING PATHWAY FROM BIG-BELLY SEAHORSE (Hippocampus abdominalis)
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빅벨리해마(Hippocampus abdominalis)에서의 Mitochondrial Heat Shock Protein 75 유전자의 특징과 발현 분석
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MOLECULAR AND FUNCTIONAL CHARACTERIZATION AND EXPRESSION ANALYSIS OF CXC CHEMOKINE RECEPTOR 3 FROM Hippocampus abdominalis
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Biochemical characterization and structural analysis of GST homologue form bigbelly seahorse (Hippocampus abdominalis)
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2016 .10
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MOLECULAR CHARACTERIZATION AND TRANSCRIPTIONAL ANALYSIS OF A COPPER/ZINC SOD (CuZnSOD) AND A MANGANESE SOD (MnSOD), IDENTIFIED IN SEAHORSE (Hippocampus abdominalis)
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식용 해마(Hippocampus abdominalis) 유래 펩신 가수분해물의 In vitro와 In vivo에서의 항산화 효능
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MOLECULAR IDENTIFICATION, BIOCHEMICAL CHARACTERIZATION AND EX PRESSION ANALYSIS OF PEROXIREDOXINE 4 FROM BIG BELLY SEAHORS E (Hippocampus abdominalis)
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2019 .05
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SEAHORSE DISTRIBUTION AND AQUACULTURE IN KOREA
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Effects of enzymatic hydrolysate from seahorse Hippocampus abdominalis on testosterone secretion from TM3 Leydig cells and in male mice
Applied Biological Chemistry
2016 .01
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Molecular cloning characterization CXCL chemokine from Hippocampus abdominalis
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Anti-fatigue activity of a mixture of seahorse (Hippocampus abdominalis) hydrolysate and red ginseng
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