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논문 기본 정보

자료유형
학술저널
저자정보
So-Hee Son (Korea Research Institute of Chemical Technology (KRICT)) Jin Kang (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) YuJin Shin (Sungkyunkwan University) ChaeYoung Lee (Sungkyunkwan University) Bong Hyun Sung (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) Ju Young Lee (Korea Research Institute of Chemical Technology (KRICT)) Wonsik Lee (Sungkyunkwan University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.48 No.2
발행연도
2024.3
수록면
140 - 148 (9page)

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초록· 키워드

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Synthetic biology approaches offer potential for large-scale and sustainable production of natural products with bioactive potency, including ginsenosides, providing a means to produce novel compounds with enhanced therapeutic properties. Ginseng, known for its non-toxic and potent qualities in traditional medicine, has been used for various medical needs. Ginseng has shown promise for its antioxidant and neuroprotective properties, and it has been used as a potential agent to boost immunity against various infections when used together with other drugs and vaccines. Given the increasing demand for ginsenosides and the challenges associated with traditional extraction methods, synthetic biology holds promise in the development of therapeutics. In this review, we discuss recent developments in microorganism producer engineering and ginsenoside production in microorganisms using synthetic biology approaches.

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ABSTRACT
1. Introduction
2. Synthetic biology approaches in natural product production
3. Modular production of natural products: polyketides and nonribosomal peptides
4. Sustainable production of ginsenosides by synthetic metabolic engineering strategies
5. Conclusion
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