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학술저널
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한원호 (국립암센터 외과) 이재훈 (Department of Critical Care Medicine National Cancer Center Goyang Korea) Chun June Young (Department of Internal Medicine National Cancer Center Goyang Korea.) 최영주 (Department of Internal Medicine National Cancer Center Goyang Korea) 김유석 (Department of Critical Care Medicine National Cancer Center Goyang Korea) 한미라 (Biostatistics Collaboration Team National Cancer Center Goyang Korea) 김지희 (Department of Critical Care Medicine National Cancer Center Goyang Korea)
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care 제38권 제1호
발행연도
2023.2
수록면
41 - 48 (8page)
DOI
10.4266/acc.2022.01235

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Background Predicting the length of stay (LOS) for coronavirus disease 2019 (COVID-19) patients in the intensive care unit (ICU) is essential for efficient use of ICU resources. We analyzed the clinical characteristics of patients with severe COVID-19 based on their clinical care and determined the predictive factors associated with prolonged LOS. Methods We included 96 COVID-19 patients who received oxygen therapy at a high-flow nasal cannula level or above after ICU admission during March 2021 to February 2022. The demographic characteristics at the time of ICU admission and results of severity analysis (Sequential Organ Failure Assessment [SOFA], Acute Physiology and Chronic Health Evaluation [APACHE] II), blood tests, and ICU treatments were analyzed using a logistic regression model. Additionally, blood tests (C-reactive protein, D-dimer, and the PaO2 to FiO2 ratio [P/F ratio]) were performed on days 3 and 5 of ICU admission to identify factors associated with prolonged LOS. Results Univariable analyses showed statistically significant results for SOFA score at the time of ICU admission, C-reactive protein level, high-dose steroids, mechanical ventilation (MV) care, continuous renal replacement therapy, extracorporeal membrane oxygenation, and prone position. Multivariable analysis showed that MV care and P/F ratio on hospital day 5 were independent factors for prolonged ICU LOS. For D-dimer, no significant variation was observed at admission; however, after days 3 and 5 days of admission, significant between-group variation was detected. Conclusions MV care and P/F ratio on hospital day 5 are independent factors that can predict prolonged LOS for COVID-19 patients.

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