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논문 기본 정보

자료유형
학술저널
저자정보
정보경 (단국대학교) 박은지 (단국대학교 의학레이저연구센터) 김선규 (동남보건대학교) 김재경 (단국대학교)
저널정보
아태인문사회융합기술교류학회 아시아태평양융합연구교류논문지 아시아태평양융합연구교류논문지 제9권 제5호
발행연도
2023.5
수록면
601 - 610 (10page)
DOI
http://dx.doi.org/10.47116/apjcri.2023.05.50

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초록· 키워드

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Assessing biomarker levels during diagnosis may be useful for predicting disease severity when formulating patient care plans. Especially, C-reactive protein (CRP) levels are often used to indicate disease severity and to monitor the response of coronavirus disease (COVID-19) patients to treatment. Similarly, an elevated erythrocyte sedimentation rate (ESR) and white blood cell (WBC) count have been reported as indicators and predictors of disease severity. This retrospective study compared immune indicators, including CRP, ESR, and WBC count, in COVID-19 patients and control group with a standard age of approximately 50 years. Data analysis was performed for patients with COVID-19 hospitalized for two weeks in Gyeonggi Provincial Medical Center Anseong Hospital, South Korea between April and October 2020 and healthy controls who underwent a health checkup in January 2020. Two groups of patients were formed based on the collected data from electronic medical records: younger (<50 years) and older adults (≥50 years). CRP levels and ESR were elevated in both young people and older adults with COVID-19. In contrast, the WBC count were decreased in young people and increased in older adults with COVID-19. Compared to control group, individuals diagnosed with COVID-19 exhibited greater CRP and ESR, with more pronounced differences observed in older adults relative to younger ones. This study provides important data on age-specific immune indicators of COVID-19 by comparing and analyzing immune indicators in individuals with a standard age of approximately 50 years. The findings can also help understand diagnostic test results and characterize viral infection at a specific time, facilitating diagnosis of COVID-19, treatment of the disease, and prediction of patient response. These values may also be useful in assessing and responding to outbreaks of similar viral diseases.

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