지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.6
- 수록면
- 96 - 104 (9page)
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초록· 키워드
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Background: Computed tomography (CT) venography is useful in determining the causes of lower-extremity edema in patients with cancer as it provides extensive anatomical information about reversible causes of edema, such as deep vein thrombosis (DVT) and extrinsic venous compression (EVC). D-dimer levels are routinely used to diagnose DVT in patients with cancer who have lower-extremity edema, although they are often elevated in patients with advanced cancer due to various causes, making it less clinically efficient. This study evaluated the clinical course of patients with advanced cancer with lower-extremity edema and elevated levels of D-dimer who underwent CT venography.
Methods: We retrospectively reviewed the medical records of 77 patients with advanced cancer who underwent CT venography due to lowerextremity edema and elevated D-dimer levels. We also examined the CT venography findings validated by radiologists and the patients’ clinical course.
Results: CT venography revealed that 33 patients (42.9%) had DVT, while 22 (28.6%) had EVC and soft-tissue edema. The DVT group had the highest mean D-dimer titer, although there was no significant difference among the groups. Anticoagulants were administered to 60.6% (n=20) of the patients with DVT, while 22.7% (n=5) of the patients with EVC underwent stent insertion.
Conclusion: EVC was diagnosed using CT venography in 28.6% of the patients with advanced cancer, lower-extremity edema, and elevated D-dimer levels. Our data suggest that diagnosing reversible causes of lower-extremity edema might improve patients’ quality of life through appropriate interventional treatment, even in a hospice or palliative care setting.
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