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논문 기본 정보

자료유형
학술저널
저자정보
Mi Jin Kim (Seoul National University) Hyun Su Kim (Dongguk University) Young-Hwa Jung (Dongguk University) Chang Won Choi (Seoul National University Bundang Hospital) Chang Won Choi (Seoul National University Bundang Hospital)
저널정보
대한신생아학회 Neonatal medicine Neonatal medicine 제30권 제2호
발행연도
2023.5
수록면
49 - 54 (6page)

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Purpose: Infants in the neonatal intensive care unit (NICU) often show cardiorespiratory deterioration during gavage feeding. We aimed to determine whether slow infusion intermittent feeding (SIIF) can reduce respiratory deterioration during gavage feeding in preterm infants in the NICU. Methods: Data on preterm infants whose gavage feeding method was changed to SIIF (1-hour infusion with an infusion pump and 2-hour rest within a 3-hour interval) from bolus gravity feeding (2- or 3-hour interval) due to feeding-associated cardiorespiratory deterioration were retrospectively reviewed. A significant cardiorespiratory event was defined as a saturation level below 80% or heart rate below 80 bpm. We compared the frequency of cardiorespiratory events and the level of respiratory support 24 hours before and after the application of SIIF. Results: A total of 34 infants were enrolled and analyzed. The total frequency of desaturation or bradycardia significantly decreased after SIIF application (8.94 vs. 5.03, P=0.001). The frequency of feeding-related bradycardia and desaturation also significantly decreased (4.15 vs. 1.68, P=0.008). Out of 34 patients, 11 (32.4%) had a decreased level of ventilator support within 1 day after SIIF. The respiratory severity scores of the 10 patients who received invasive ventilator support decreased significantly after SIIF (5.24 vs. 4.59, P=0.032). Conclusion: SIIF significantly decreased gavage feeding-associated cardiorespiratory events and reduced respiratory support in approximately one-third of subjects. Therefore, SIIF may be a therapeutic option for gavage feed-associated respiratory deterioration in preterm infants in the NICU.

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