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논문 기본 정보

자료유형
학술저널
저자정보
Hiroaki Kusunose (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Shinsuke Koshita (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Yoshihide Kanno (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Takahisa Ogawa (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Toshitaka Sakai (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Keisuke Yonamine (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Kazuaki Miyamoto (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Fumisato Kozakai (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Hideyuki Anan (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Kazuki Endo (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Haruka Okano (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Masaya Oikawa (Departments of Surgery Sendai City Medical Center Sendai Japan) Takashi Tsuchiya (Departments of Surgery Sendai City Medical Center Sendai Japan) Takashi Sawai (Departments of Pathology Sendai City Medical Center Sendai Japan) Yutaka Noda (Departments of Gastroenterology Sendai City Medical Center Sendai Japan) Kei Ito (Departments of Gastroenterology Sendai City Medical Center Sendai Japan)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제56권 제3호
발행연도
2023.5
수록면
353 - 366 (14page)
DOI
10.5946/ce.2022.021

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초록· 키워드

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Background/Aims: This study aimed to clarify the efficacy and safety of pancreatic duct lavage cytology combined with a cell-block method (PLC-CB) for possible pancreatic ductal adenocarcinomas (PDACs). Methods: This study included 41 patients with suspected PDACs who underwent PLC-CB mainly because they were unfit for undergoing endoscopic ultrasonography-guided fine needle aspiration. A 6-Fr double lumen catheter was mainly used to perform PLC-CB. Final diagnoses were obtained from the findings of resected specimens or clinical outcomes during surveillance after PLC-CB. Results: Histocytological evaluations using PLC-CB were performed in 87.8% (36/41) of the patients. For 31 of the 36 patients, final diagnoses (invasive PDAC, 12; pancreatic carcinoma in situ, 5; benignancy, 14) were made, and the remaining five patients were excluded due to lack of surveillance periods after PLC-CB. For 31 patients, the sensitivity, specificity, and accuracy of PLC-CB for detecting malignancy were 94.1%, 100%, and 96.8%, respectively. In addition, they were 87.5%, 100%, and 94.1%, respectively, in 17 patients without pancreatic masses detectable using endoscopic ultrasonography. Four patients developed postprocedural pancreatitis, which improved with conservative therapy. Conclusions: PLC-CB has an excellent ability to detect malignancies in patients with possible PDACs, including pancreatic carcinoma in situ.

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