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논문 기본 정보

자료유형
학술저널
저자정보
Suhua Yao (Dali University) Xiaoting Chen (Dali University) Lian Qian (Dali University) Shizheng Sun (Dali University) Chunjing Zhao (Dali University) Zongkai Bai (Dali University) Zhaofang Chen (Dali University) Youcong Wu (Dali University)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases Parasites, Hosts and Diseases Vol.61 No.2
발행연도
2023.5
수록면
183 - 194 (12page)

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초록· 키워드

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Balamuthia mandrillaris amebic encephalitis (BAE) can cause a fatal condition if diagnosis is delayed or effective treatment is lacking. Patients with BAE have been previously reported in 12 provinces of China, with skin lesions being the primary symptom and encephalitis developing after several years. However, a significantly lower number of cases has been reported in Southwest China. Here we report an aggressive BAE case of a 64-year-old woman farmer with a history of skin lesions on her left hand. She was admitted to our hospital due to symptoms of dizziness, headache, cough, vomiting, and gait instability. She was initially diagnosed with syphilitic meningoencephalitis and received a variety of empirical treatment that failed to improve her symptoms. Finally, she was diagnosed with BAE combined with amebic pneumonia using next-generation sequencing (NGS), qRT-PCR, sequence analysis, and imaging studies. She died approximately 3 weeks after the onset. This case highlights that the rapid development of encephalitis can be a prominent clinical manifestation of Balamuthia mandrillaris infection.

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Abstract
Introduction
Case Description
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