메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Yoon Tae-gun (Yongin University Yongin Republic of Korea) Hwang Byong-yong (Yongin University Yongin Republic of Korea) Ahn Sang-hyun (Semyung University Jecheon Republic of Korea) Kim Ki-bong (Pusan National University Pusan Republic of Korea)
저널정보
J-INSTITUTE Kinesiology Kinesiology Vol.1 No.2
발행연도
2016.12
수록면
1 - 5 (5page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Rheumatoid arthritis(RA) can occur in persons of all ages and of both sexes. Diverse studies recommend exercise to help diminish pain from RA symptoms. Although exercise for patients with RA is an effective therapy to improve functional impairment, patients experience reluctance to exercise because of pain. Several studies have focused on investigating the treatments for this disease. However, RA is currently an incurable disease because its pathogenic cause is still unclear. In view of the complex considerations, the treatment of RA with exercise requires more effective research for developing therapies with proven stability. For example, natural compounds are potential therapeutic agents and candidates as sports nutrition supplements. In the present study, we aimed to find a candidate sport nutrition supplement from natural compounds such as foods and tea. Lonicerae flos(LF) has been widely used in Korean traditional medicine and as a tea material. Therefore, we evaluated the effect of LF extract on an RA model. First, we found that the mRNA expression of macrophage migration inhibitory factor(MIF), cyclooxygenase-2(COX-2), and matrix metalloproteinase-9(MMP-9) in synoviocytes stimulated with phorbol-12-myristate-13-acetate was decreased by LF treatment(0.4?1.0 mg/mL). Furthermore, the distribution of MIF-, COX-2-, and MMP-9-positive cells in mice with collagen-induced arthritis treated with LF(45 mg/kg) was remarkably decreased. These data likely indicate that LF may act as an anti-inflammatory agent and may be a potential compound for the development of useful agents for RA treatment.

목차

등록된 정보가 없습니다.

참고문헌 (5)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0