지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Patients admitted to an intensive care unit (ICU) are at high risk for prescribingerrors. The presence of a pharmacist in the ICU has been shown to reduce the incidence of prescribingerrors, the length of stay and to prevent adverse drug events (ADEs). Since 25 March2013, pharmacists have started to participate in monitoring of medication and in rounding in thesurgical ICU (SICU) at the Samsung Medical Center. The purpose of this study was to evaluatethe effects of a pharmacist’s role in the SICU.
A historical case control study was conducted by a retrospective electronic medical record chartreview. Therefore, patients were assigned to either the control group (patients who were admittedto the SICU from 25 March to 30 June 2012) or the intervention group (patients who wereadmitted to the SICU from 25 March to 30 June 2013). Demographic features, frequency andtypes of inappropriate prescribing, ADEs and length of stay in SICU were reviewed in both groups.
A total of 8,523 medications for 151 patients in the intervention group and a total of 9,642 medicationprofiles for 160 patients in the control group were reviewed in each group. There were57(83%) drug-related interventions in the intervention group and 12(17%) information serviceswith pharmacist intervention. Thirty eight (67%) of drug-related interventions were found for anadjustment of the dosage regimen according to organ dysfunctions. The incidence of inappropriateprescribing per 1,000 monitored patient-days in was much lower in the intervention groupthan in the control group: 1.48 vs. 104.22 p<0.001. In the control group, the majority of inappropriateprescribing counted for an overdose of antibiotics. One preventable ADE occurred in thecontrol group. However, there were none in the intervention group. The length of stay in the ICUtended to be shorter and the number of hospital days to be smaller in the intervention group thanin the control group (3 days vs. 4 days. p=0.089, 16 days vs. 17 days, p=0.059).
The intervention of a pharmacist in the SICU was associated with significant reductions ininappropriate prescribing and the number of ADEs.
목차
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참고문헌 (15)
참고문헌 신청
Joanna E Klopotowska / 2010 / On-ward participation of a hospital pharmacist in a Dutch intensive care unit reduces prescribing errors and related patient harm : an intervention study / Crit care 14:174~186
Montazeri, Cook / 1994 / Impact of a clinical pharmacist in a multidisplinary intensive care unit / Crit care med 22:1044~1048
Vargas E. / 2003 / Effect of adverse drug reactions on length of stay in surgical intensive care units / Crit care med 31:694~698
LL Leape / 1999 / Pharmacist participation on physician rounds and adverse drug events in the intensive care unit / JAMA 282:267~270
Chuang L.C / 1994 / Impact of a clinical pharmacist on cost saving and cost avoidance in drug therapy in an intensive care unit / Hosp Pharm 29:214~221
Montazeri, Cook / 1994 / Impact of a clinical pharmacist in a multidisplinary intensive care unit / Crit care med 22:1044~1048
Vargas E. / 2003 / Effect of adverse drug reactions on length of stay in surgical intensive care units / Crit care med 31:694~698
LL Leape / 1999 / Pharmacist participation on physician rounds and adverse drug events in the intensive care unit / JAMA 282:267~270
Chuang L.C / 1994 / Impact of a clinical pharmacist on cost saving and cost avoidance in drug therapy in an intensive care unit / Hosp Pharm 29:214~221
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