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논문 기본 정보

자료유형
학술저널
저자정보
Noriyuki Tawara (Japan Health Care College) Atsushi Nishiyama (Japan Health Care College)
저널정보
대한자기공명의과학회 Investigative Magnetic Resonance Imaging Investigative Magnetic Resonance Imaging 제20권 제4호
발행연도
2016.12
수록면
207 - 214 (8page)
DOI
https://doi.org/10.13104/imri.2016.20.4.207

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Purpose: The purpose of this study was to investigate the effect of the number of measurement points on the calculation of transverse relaxation time (T2) with a focus on muscle T2. Materials and Methods: This study assumed that muscle T2 was comprised of a single component. Two phantom types were measured, 1 each for long (“phantom”) and short T2 (“polyvinyl alcohol gel”). Right calf muscle T2 measurements were conducted in 9 healthy male volunteers using multiple-spin-echo magnetic resonance imaging. For phantoms and muscle (medial gastrocnemius), 5 regions of interests were selected. All region of interest values were expressed as the mean ± standard deviation. The T2 effective signal-ratio characteristics were used as an index to evaluate the magnetic resonance image quality for the calculation of T2 from T2- weighted images. The T2 accuracy was evaluated to determine the T2 reproducibility and the goodness-of-fit from the probability Q. Results: For the phantom and polyvinyl alcohol gel, the standard deviation of the magnetic resonance image signal at each echo time was narrow and monoexponential, which caused large variations in the muscle T2 decay curves. The T2 effective signal-ratio change varied with T2, with the greatest decreases apparent for a short T2. There were no significant differences in T2 reproducibility when > 3 measurement points were used. There were no significant differences in goodnessof- fit when > 6 measurement points were used. Although the measurement point evaluations were stable when > 3 measurement points were used, calculation of T2 using 4 measurement points had the highest accuracy according to the goodnessof- fit. Even if the number of measurement points was increased, there was little improvement in the probability Q. Conclusion: Four measurement points gave excellent reproducibility and goodnessof- fit when muscle T2 was considered mono-exponential.
#Transverse relaxation time #Skeletal muscle #Number of measurement points #Goodness-of-fit #T2 effective signal-ratio

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참고문헌 (25)

참고문헌 신청
Fleckenstein JL / 1988 / Acute effects of exercise on MR imaging of skeletal muscle in normal volunteers / AJR Am J Roentgenol 151:231~237 google schola Fleckenstein JL / 1993 / Muscle proton T2 relaxation times and work during repetitive maximal voluntary exercise / J Appl Physiol (1985) 74:2855~2859 google schola Saab G / 2000 / Effects of exercise on muscle transverse relaxation determined by MR imaging and in vivo relaxometry / J Appl Physiol (1985) 88:226~233 google schola Morvan D / 1995 / Simultaneous measurements of diffusion and transverse relaxation in exercising skeletal muscle / Magn Reson Imaging 13:943~948 google schola Price TB / 1995 / Changes in magnetic resonance transverse relaxation times of two muscles following standardized exercise / Med Sci Sports Exerc 27:1421~1429 google schola

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