지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 163 - 169 (7page)
- DOI
- 10.35420/jcohns.2021.32.3.163
이용수
초록· 키워드
오류제보하기
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection, is rapidly spreading worldwide. Oral manifestations of COVID-19, including sore throat, loss of taste, dry mouth, and ulceration have been widely reported. SARS-CoV-2 enters host cells using angiotensin- converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). Therefore, high levels of expression of ACE2 and TMPRSS2 may enhance SARS-CoV-2 invasion. ACE2 and TMPRSS2 were expressed in the taste bud and intermediate layer of the squamous epithelia of tongue papillae. Additionally, ACE2 and TMPRSS2 were co-expressed in the ductal epithelium and acinar cells of salivary glands and in the neuronal cell body of trigeminal ganglia. SARS-CoV-2 directly invades the oral taste buds, causing loss of taste. Additionally, the possibility of neuroinvasion innervation of taste bud cells cannot be excluded. SARS-CoV-2 spreads around the suprabasal areas of the oral squamous epithelia, and invades the trigeminal nerve, resulting in oral manifestations. SARS-CoV-2 can directly invade the parotid and submandibular glands, as well as minor salivary glands, through the duct orifice. This may lead to sialadenitis and salivary contamination.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Zhu N / 2020 / A novel coronavirus from patients with pneumonia in China, 2019 / N Engl J Med 382(8):727~733
Epidemiology Working Group for NCIP Epidemic Response / 2020 / The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China / Zhonghua Liu Xing Bing Xue Za Zhi 41(2):145~151
Guan WJ / 2020 / China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China / N Engl J Med 382(18):1708~1720
Mercante G / 2020 / Prevalence of taste and smell dysfunction in coronavirus disease 2019 / JAMA Otolaryngol Head Neck Surg 146(8):723~728
Amorim Dos Santos J / 2021 / Oral manifestations in patients with COVID-19 : a living systematic review / J Dent Res 100(2):141~154
Epidemiology Working Group for NCIP Epidemic Response / 2020 / The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China / Zhonghua Liu Xing Bing Xue Za Zhi 41(2):145~151
Guan WJ / 2020 / China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China / N Engl J Med 382(18):1708~1720
Mercante G / 2020 / Prevalence of taste and smell dysfunction in coronavirus disease 2019 / JAMA Otolaryngol Head Neck Surg 146(8):723~728
Amorim Dos Santos J / 2021 / Oral manifestations in patients with COVID-19 : a living systematic review / J Dent Res 100(2):141~154
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19
Annals of Laboratory Medicine
2021 .01
-
Oral symptom manifestations in COVID-19 patients: Gustatory and saliva secretion disorders and pathogenetic hypotheses
International Journal of Oral Biology
2024 .09
-
SARS-CoV-2-Specific T Cell Responses in Patients with COVID-19 and Unexposed Individuals
Immune Network
2021 .02
-
An overview of the gut side of the SARS-CoV-2 infection
Intestinal research
2021 .10
-
Experimental Animal Models of Coronavirus Infections: Strengths and Limitations
Immune Network
2021 .04
-
코로나바이러스19 감염증과 안지오텐신전환효소2
대한내과학회지
2020 .08
-
Lessons Learned from SARS-CoV and MERS-CoV: Preparation for SARS-CoV-2 induced COVID-19
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2020 .06
-
Can sunlight affect COVID-19 outcomes? What is the available evidence?
Clinical and Experimental Emergency Medicine
2021 .09
-
Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean Red Ginseng
Journal of Ginseng Research
2023 .01
-
코로나바이러스감염증-19의 바이러스 (SARS-CoV-2) 특징, 전파 및 임상 양상
Pediatric Infection and Vaccine
2020 .01
-
코로나바이러스 감염병-19와 갑상선 질환
임상이비인후과
2021 .12
-
Virus Isolation from the First Patient with SARS-CoV-2 in Korea
Journal of Korean Medical Science
2020 .01
-
코로나바이러스감염증-19(SARS-CoV-2 감염증)의 임상 양상과 치료
임상이비인후과
2020 .01
-
Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea
Osong Public Health and Research Persptectives
2020 .01
-
Isolation and Genomic Analyses of an Early SARS-CoV-2 Strains from the 2020 Epidemic in Gwangju, South Korea
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2021 .09
-
A mouse model for SARS-CoV-2 infection using adeno-associated virus encoding hACE2
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Severe acute respiratory syndrome coronavirus-2 대유행 중 알레르기 환자의 진료
Allergy Asthma & Respiratory Diseases
2021 .01
-
Newly Emerging Human Coronaviruses: Animal Models and Vaccine Research for SARS, MERS, and COVID-19
Immune Network
2020 .08
-
Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target
Immune Network
2021 .02
-
Empirical Treatment and Prevention of COVID-19
Infection and Chemotherapy
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0