지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 83 - 90 (8page)
- DOI
- https://doi.org/10.17945/kjbt.2021.32.2.83
이용수
초록· 키워드
오류제보하기
Background: Severe fever with thrombocytopenia syndrome (SFTS) is a novel infection caused by the tick-borne SFTS virus. More than 200 patients are reported every year in Korea, but there is no established treatment. In patients with SFTS, therapeutic plasma exchange (TPE) can be applied.
Methods: Clinical and laboratory characteristics of patients diagnosed with SFTS who underwent TPE were analyzed. The factors that can differentiate the prognosis between the patients who recovered after TPE and those who died were analyzed.
Results: Ten patients were diagnosed with SFTS and treated with TPE. The mean age was 70.8 (49?85) years, with three men and seven females. The laboratory findings showed a decrease in white blood cell (WBC) count, platelet count, and serum albumin and an increase in AST, ALT, LDH, and CK levels. Patients performed an average of three (2∼4) TPE procedures at intervals of 1∼2 days, three of whom died. Compared to the results at admission, the WBC counts increased after TPE, and the platelet counts remained unchanged. The AST, LDH, and CK levels decreased by 2∼6 fold in the recovered patients and increased in those who died. Among them, the change in LDH was statistically significant between the two groups (P=0.0227).
Conclusion: TPE has been used as an adjuvant treatment in SFTS patients who do not have a definitive treatment to date. Additional studies, including small-scale studies such as this study, will be needed to establish the timing, interval, and predictive factors of the effect of TPE. (Korean J Blood Transfus 2021;32:83-90)
목차
등록된 정보가 없습니다.
참고문헌 (5)
참고문헌 신청
오원섭 / 2017 / Effect of Early Plasma Exchange on Survival in Patients with Severe Fever with Thrombocytopenia Syndrome: A Multicenter Study / Yonsei Medical Journal 58(4):867~871
유정래 / 2019 / Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome / The Korean Journal of Internal Medicine 34(4):902~909
김선형 / 2014 / 중증열성혈소판감소증후군 환자에서의 치료적 혈장교환술 시행 경험 / 대한수혈학회지 25(3):211~217
유정래 / 2018 / 중증열성혈소판감소증후군(SFTS) 환자에 대한 고찰: 현재까지 연구된 치료법을 중점으로 / 대한수혈학회지 29(2):117~129
김계형 / 2014 / 중증열성혈소판감소증후군 / 대한내과학회지 86(3):271~276
유정래 / 2019 / Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome / The Korean Journal of Internal Medicine 34(4):902~909
김선형 / 2014 / 중증열성혈소판감소증후군 환자에서의 치료적 혈장교환술 시행 경험 / 대한수혈학회지 25(3):211~217
유정래 / 2018 / 중증열성혈소판감소증후군(SFTS) 환자에 대한 고찰: 현재까지 연구된 치료법을 중점으로 / 대한수혈학회지 29(2):117~129
김계형 / 2014 / 중증열성혈소판감소증후군 / 대한내과학회지 86(3):271~276
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