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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.9
- 수록면
- 91 - 98 (8page)
- DOI
- https://doi.org/10.13041/jpvm.2018.42.3.91
이용수
초록· 키워드
오류제보하기
Epizootic HPAIV, H5N6, and H5N8 infections produced severe loss in poultry and wild birds in the Republic of Korea from 2016 to 2017. But pathological lesions and antigen distribution of the novel HPAIV H5N6 clade 2.3.4.4 in natural cases have been rarely reported. Herein, we describe the pathological lesions and antigen localization in chickens (layer and Korean native), ducks, and Japanese quail naturally infected by HPAIV H5N6. Grossly, severe reddening, swelling, and some necrotic foci, which were similar to septicemia or viremia, were observed in skin and many visceral organs including trachea, lung, liver, spleen, and pancreas. Histopathologically, pulmonary congestion and edema, as well as necrotizing hepatitis, splenitis, pancreatitis, myocarditis, and encephalitis were observed. Immunohistochemically, numerous HPAIV antigens were detected in necrotic parenchymal cells and in blood vessels of the respiratory, lymphoid, digestive, urinary, nervous, and cardiovascular systems. The results indicate that HPAIV H5N6 spread to the entire body via blood and caused severe damage throughout the entire body. The HPAI H5N6 clade 2.3.4.4 virus was isolated from samples of all four cases.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Bae YJ / 2015 / Pathological evaluation of natural cases of a highly pathogenic avian influenza virus, subtype H5N8, in broiler breeders and commercial layers in South Korea / Avian Dis. 59:175~182
Bi Y / 2016 / Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014 / Scientific reports 6:29888
Brojer C. / 2015 / Pathogenicity and tissue tropism of currently circulating highly pathogenic avian influenza A virus (H5N1; clade 2.3.2) in tufted ducks (Aythya fuligula) / Vet Microbiol 180:273~280
Butler J / 2016 / Novel Reassortant H5N6 Influenza A Virus from the Lao People's Democratic Republic Is Highly Pathogenic in Chickens / PLoS One 11:e0162375
Carnaccini S / 2017 / Pathology and Tissue Distribution of an LPAI H5N8 of North American Lineage Isolated from an Outbreak in Commercial Japanese Quail (Coturnix c. japonica) in the Central Valley of California / Avian Dis 61:70~76
Bi Y / 2016 / Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014 / Scientific reports 6:29888
Brojer C. / 2015 / Pathogenicity and tissue tropism of currently circulating highly pathogenic avian influenza A virus (H5N1; clade 2.3.2) in tufted ducks (Aythya fuligula) / Vet Microbiol 180:273~280
Butler J / 2016 / Novel Reassortant H5N6 Influenza A Virus from the Lao People's Democratic Republic Is Highly Pathogenic in Chickens / PLoS One 11:e0162375
Carnaccini S / 2017 / Pathology and Tissue Distribution of an LPAI H5N8 of North American Lineage Isolated from an Outbreak in Commercial Japanese Quail (Coturnix c. japonica) in the Central Valley of California / Avian Dis 61:70~76
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